Evidence map›Paper›PMID 32458781›Full record

ArticleThe American journal of tropical medicine and hygiene2020

Exposure to N,N-Diethyl-Meta-Toluamide Insect Repellent and Human Health Markers: Population Based Estimates from the National Health and Nutrition Examination Survey.

Zuhair M Haleem, Sandhya Yadav, Minor L Cushion, Rebecca J Tanner, Peter J Carek, Arch G Mainous

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Repellents againstFrontiers in insect science · 2024
    Review
  7. Article
  8. Comparison of in vitro Killing Effect ofClinical, cosmetic and investigational dermatology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Zuhair M Haleem1Department of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Sandhya Yadav1Department of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Minor L Cushion1Department of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Rebecca J Tanner1Department of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
Peter J Carek2Department of Community Health and Family Medicine, University of Florida, Gainesville, Florida.
Arch G Mainous1Department of Health Services Research, Management, and Policy, University of Florida, Gainesville, Florida.
University of Florida · USUniversity of Florida Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

N,N-diethyl-meta-toluamide (DEET) is one of the most commonly used insect repellants in the United States, yet the existing literature regarding DEET's potential deleterious impact on humans is mixed and is based mostly on case reports. The primary aim of this study was to address this lack of population-based evidence of the effects of DEET exposure on human health in the United States. Our primary outcome measures were biomarkers related to systemic inflammation (high sensitivity C-reactive protein), immune function (lymphocyte), liver function (aspartate aminotransferase, alanine aminotransferase, and γ-glutamyl transferace), and kidney function (estimated glomerular filtration rate). We analyzed data from the population-based National Health and Nutrition Examination Survey, 2015-2016, and identified 1,205 patients (age 20+ years) who had DEET metabolite levels recorded at or above detection limits. A Pearson correlation was used to assess the relationship between DEET metabolite, and each biomarker found there was no significant correlation. Thus, there is no evidence that DEET exposure has any impact on the biomarkers identified.

Indexed as

Glomerular Filtration RateLymphocyte CountAdultAgedAlanine TransaminaseAspartate AminotransferasesBiomarkersC-Reactive ProteinDEETFemalegamma-GlutamyltransferaseHumansInsect RepellentsMaleMiddle AgedNutrition SurveysAlanine TransaminaseAspartate AminotransferasesBiomarkersC-Reactive ProteinDEETgamma-GlutamyltransferaseInsect Repellents

Identifiers

PMID32458781
PMCPMC7410448
OpenAlexW3032889518

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.