Evidence map›Paper›PMID 32458449›Full record

ArticleMedical physics2020

Fast acquisition with seamless stage translation (FASST) for a trimodal x-ray breast imaging system.

Ran Zhang, Amy M Fowler, Lee G Wilke, Frederick Kelcz, John W Garrett, Guang-Hong Chen, Ke Li

Abstract read
In one paragraph

Article in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ran ZhangDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Amy M FowlerDepartment of Radiology, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI, 53792, USA.
Lee G WilkeUniversity of Wisconsin Carbone Cancer Center, 600 Highland Avenue, Madison, WI, 53792, USA.
Frederick KelczDepartment of Radiology, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI, 53792, USA.
John W GarrettDepartment of Radiology, University of Wisconsin-Madison, 600 Highland Avenue, Madison, WI, 53792, USA.
Guang-Hong ChenDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.
Ke LiDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, WI, 53705, USA.

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
Multi-Contrast X-ray Breast ImagingR01EB020521 · NIBIB · UNIVERSITY OF WISCONSIN-MADISON · PI CHEN, GUANG-HONG, LI, KE · 2016 to 2020
$2.0M
NCI NIH HHS P30 CA014520NIBIB NIH HHS R01 EB020521NIH HHS P30CA014520NIH HHS R01EB020521
6 · The paper itself

Abstract

purposeA major technical obstacle to bringing x-ray multicontrast (i.e., attenuation, phase, and dark-field) imaging methodology to clinical use is the prolonged data acquisition time caused by the phase stepping procedure. The purpose of this work was to introduce a fast acquisition with seamless stage translation (FASST) technique to a prototype multicontrast breast imaging system for reduced image acquisition time that is clinically acceptable.

methodsThe prototype system was constructed based on a Hologic full-field digital mammography + digital breast tomosynthesis combination system. During each FASST acquisition process, a motorized stage holding a diffraction grating travels continuously with a constant velocity, and a train of 15 short x-ray pulses (35 ms each) was delivered by using the Zero-Degree Tomo mode of the Hologic system. Standard phase retrieval was applied to the 15 subimages without spatial interpolation to avoid spatial resolution loss. The method was evaluated using a physical phantom, a bovine udder specimen, and a freshly resected mastectomy specimen. The FASST technique was experimentally compared with single-shot acquisition methods and the standard phase stepping method.

resultsThe image acquisition time of the proposed method is 3.7 s. In comparison, conventional phase stepping took 105 s using the same prototype imaging system. The mean glandular dose of both methods was matched at 1.3 mGy. No artifacts or spatial resolution loss was observed in images produced by FASST. In contrast, the single-shot methods led to spatial resolution loss and residual moiré artifacts.

conclusionsThe FASST technique reduces the data acquisition time of the prototype multicontrast x-ray breast imaging system to 3.7 s, such that it is comparable to a clinical digital breast tomosynthesis exam.

Indexed as

Breast NeoplasmsAnimalsCattleHumansMammographyMastectomyPhantoms, ImagingRadiographyX-Raysbreast imagingmammographyphase steppingTalbot-Lau interferometerx-ray dark-field imagingx-ray phase contrast imaging

Identifiers

PMID32458449
PMCPMC7704901

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.