Evidence map›Paper›PMID 32458347›Full record

ArticleInflammation2020

Hepatoprotective Effect of Apigenin Against Liver Injury via the Non-canonical NF-κB Pathway In Vivo and In Vitro.

Shuwen Yue, Ning Xue, Honglei Li, Baosheng Huang, Zhen Chen, Xing Wang

Abstract read
PubMed Publisher
In one paragraph

Article in Inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Geraniol prevents CClToxicology reports · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Role of apigenin in targeting metabolic syndrome: A systematic review.Iranian journal of basic medical sciences · 2024
    Review
  16. Review
  17. Review
  18. Applications ofAntioxidants (Basel, Switzerland) · 2023
    Review
  19. Article
  20. Natural flavonols: actions, mechanisms, and potential therapeutic utility for various diseases.Beni-Suef University journal of basic and applied sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Shuwen Yue *Department of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China.
Ning Xue *Department of Acupuncture, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, People's Republic of China.
Honglei LiDepartment of Pharmacy, Kangda College of Nanjing Medical University, Lianyungang, Jiangsu, People's Republic of China.
Baosheng HuangDepartment of Neurosurgery, Sir Run Run Hospital, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.
Zhen ChenDepartment of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China.
Xing WangDepartment of Pharmacology, School of Pharmacy, China Pharmaceutical University, Nanjing, Jiangsu, People's Republic of China. star10000@sina.com.
China Pharmaceutical University · CNNanjing Medical University · CNJiangsu University · CN

Funding

Nanjing Medical University Science Research and Development Foundation 2016NJMU013Natural Science Foundation of Jiangsu Province BK20171064Natural Science Foundation of Jiangsu Province BK20180574Natural Science Research Fund (General Program) for the Higher Education of Jiangsu Province of China 18KJB350005Research Foundation of Jiangsu Provincial Medical Youth Talent, the Project of Inviogorating Health Care through Science, Technology and Education QNRC2016858Technology Incubator Scheme (Social Programs) of Jiangning District 2018Ca12Zhenjiang City 2017 Science and Technology Innovation Fund SH2017043
6 · The paper itself

Abstract

Apigenin, a flavonoid found in many plants, has various biological properties. We aimed to investigate the anti-inflammatory and anti-oxidative activity of apigenin against carbon tetrachloride (CCl

Indexed as

AnimalsApigeninCarbon TetrachlorideCell SurvivalChemical and Drug Induced Liver InjuryDose-Response Relationship, DrugHep G2 CellsHumansHydrogen PeroxideMaleMiceMice, Inbred ICRNF-kappa BOxidative StressSignal TransductionApigeninCarbon TetrachlorideHydrogen PeroxideNF-kappa Bapigenininflammationnon-canonical NF-κB pathwayoxidative stress

Identifiers

PMID32458347
OpenAlexW3030169983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.