Evidence map›Paper›PMID 32458219›Full record

ArticleClinical journal of gastroenterology2020

Successful treatment of hepatocellular carcinoma by laparoscopic radiofrequency ablation in a patient with hemophilia A.

Rie Goka, Naoki Morimoto, Kouichi Miura, Shunji Watanabe, Yoshinari Takaoka, Hiroaki Nomoto, Mamiko Tsukui, Takeshi Fujieda, Hiroshi Maeda, Naoto Sato and 3 more

Open access · hybridAbstract readCase Reports
PubMed Publisher
In one paragraph

Article in Clinical journal of gastroenterology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Rie Goka
Naoki Morimoto
Kouichi MiuraDivision of Gastroenterology, Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shomotsuke, Tochigi, 329-0498, Japan. miura385@jichi.ac.jp.
Shunji Watanabe
Yoshinari Takaoka
Hiroaki Nomoto
Mamiko Tsukui
Takeshi Fujieda
Hiroshi MaedaDivision of Gastroenterology, Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shomotsuke, Tochigi, 329-0498, Japan.
Naoto SatoDivision of Gastroenterology, Department of Medicine, Jichi Medical University, 3311-1 Yakushiji, Shomotsuke, Tochigi, 329-0498, Japan.
Tsukasa OhmoriDepartment of Biochemistry, Jichi Medical University, Shimotsuke, Tochigi, Japan.
Norio Isoda
Hironori Yamamoto
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Percutaneous radiofrequency ablation (RFA) is a good indication for hepatocellular carcinoma (HCC) in cases involving ≦ 3 tumors of ≦ 30 mm in size, many hepatologists are hesitant to perform the procedure for patients with hemorrhagic disorders. We herein report the successful treatment of HCC by laparoscopic RFA in a patient with hemophilia A. A 48-year-old man with moderate form of hemophilia A had a single HCC at segment 8. To perform laparoscopic RFA safely, recombinant factor VIII (rFVIII) was administered to maintain factor VIII activity (FVIII:C) > 80% on the operation day and > 40% for 6 days after the operation in accordance with the guidelines. A total of 23,000 units of rFVIII was used. Laparoscopic RFA was completed with an operation time of 105 min and < 10 mL of blood loss. As a result, blood transfusion was not required. At 2 years after the initial treatment, HCC recurred at segment 7. Under rFVIII supplementation, we performed a second laparoscopic RFA without any events. Although partial hepatectomy is the main procedure used to treat HCC in patients with hemophilia, we could reduce in total use of rFVIII, blood and operation time by laparoscopic RFA compared with those in partial hepatectomy.

Indexed as

Carcinoma, HepatocellularCatheter AblationHemophilia ALaparoscopyLiver NeoplasmsRadiofrequency AblationHumansMaleMiddle AgedNeoplasm Recurrence, LocalTreatment OutcomeHemophiliaHepatocellular carcinomaLaparoscopyRadiofrequency ablation

Identifiers

PMID32458219
OpenAlexW3031939736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.