Evidence map›Paper›PMID 32458157›Full record

ArticleEuropean journal of nutrition2021

Dietary riboflavin deficiency induces ariboflavinosis and esophageal epithelial atrophy in association with modification of gut microbiota in rats.

Feng Pan, Ling-Li Zhang, Hong-Jun Luo, Ye Chen, Lin Long, Xuan Wang, Pei-Tong Zhuang, En-Min Li, Li-Yan Xu

Abstract read
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In one paragraph

Article in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  9. Effects ofFoods (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Feng PanKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China.
Ling-Li ZhangDepartment of Experimental Animal Center, Shantou University Medical College, Shantou, 515041, China.
Hong-Jun LuoBioanalytical Laboratory, Shantou University Medical College, Shantou, 515041, China.
Ye ChenKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China.
Lin LongKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China.
Xuan WangKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China.
Pei-Tong ZhuangKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China.
En-Min LiKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China. nmli@stu.edu.cn.
Li-Yan XuKey Laboratory of Molecular Biology for High Cancer Incidence Coastal Chaoshan Area, Shantou University Medical College, Shantou, 515041, China. lyxu@stu.edu.cn.
Shantou University Medical College · CNShantou University · CN

Funding

DeGregorio Family Foundation (US) 2016YFC0901400Natural Science Foundation of China-Guangdong Joint Fund No. U1301227
6 · The paper itself

Abstract

purposeRiboflavin deficiency causes ariboflavinosis, a common nutritional deficiency disease. The purpose of this study is to investigate the effects of riboflavin deficiency on the important internal organs and its potential mechanisms.

methodsExperiment 1, male F344 rats were randomly assigned to R

resultsRiboflavin deficiency induced ariboflavinosis (R

conclusionsRiboflavin deficiency induces ariboflavinosis and esophageal epithelial atrophy by modulating the gut microbiota, and offers new Queryinsight into riboflavin deficiency and esophageal lesions.

Indexed as

EsophagusGastrointestinal MicrobiomeRiboflavin DeficiencyAnimalsAtrophyMaleRatsRats, Inbred F344RiboflavinRNA, Ribosomal, 16SRiboflavinRNA, Ribosomal, 16SAriboflavinosisEsophageal epithelial atrophyGenomic instabilityGut microbiotaXenobiotic biodegradation

Identifiers

PMID32458157
OpenAlexW3030100217

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.