Evidence map›Paper›PMID 32457916›Full record

ReviewFrontiers in nutrition2020

Bioactive Phenolic Compounds From Agri-Food Wastes: An Update on Green and Sustainable Extraction Methodologies.

Lucia Panzella, Federica Moccia, Rita Nasti, Stefania Marzorati, Luisella Verotta, Alessandra Napolitano

Abstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 118 papers.

0numbers the graph read from it
0cells of the map it votes in
118citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

118 citing papers in PubMed.

  1. Pomegranate (Veterinary sciences · 2026
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  12. Unveiling the Pharmacological Effects ofCentral nervous system agents in medicinal chemistry · 2026
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  18. Optimisation of Phenolic Compound Extraction fromAntioxidants (Basel, Switzerland) · 2025
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  20. Review

58 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lucia PanzellaDepartment of Chemical Sciences, University of Naples "Federico II", Naples, Italy.
Federica MocciaDepartment of Chemical Sciences, University of Naples "Federico II", Naples, Italy.
Rita NastiDepartment of Environmental Science and Policy, Università degli Studi di Milano, Milan, Italy.
Stefania MarzoratiDepartment of Environmental Science and Policy, Università degli Studi di Milano, Milan, Italy.
Luisella VerottaDepartment of Environmental Science and Policy, Università degli Studi di Milano, Milan, Italy.
Alessandra NapolitanoDepartment of Chemical Sciences, University of Naples "Federico II", Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phenolic compounds are broadly represented in plant kingdom, and their occurrence in easily accessible low-cost sources like wastes from agri-food processing have led in the last decade to an increase of interest in their recovery and further exploitation. Indeed, most of these compounds are endowed with beneficial properties to human health (e.g., in the prevention of cancer and cardiovascular diseases), that may be largely ascribed to their potent antioxidant and scavenging activity against reactive oxygen species generated in settings of oxidative stress and responsible for the onset of several inflammatory and degenerative diseases. Apart from their use as food supplements or as additives in functional foods, natural phenolic compounds have become increasingly attractive also from a technological point of view, due to their possible exploitation in materials science. Several extraction methodologies have been reported for the recovery of phenolic compounds from agri-food wastes mostly based on the use of organic solvents such as methanol, ethanol, or acetone. However, there is an increasing need for green and sustainable approaches leading to phenolic-rich extracts with low environmental impact. This review addresses the most promising and innovative methodologies for the recovery of functional phenolic compounds from waste materials that have appeared in the recent literature. In particular, extraction procedures based on the use of green technologies (supercritical fluid, microwaves, ultrasounds) as well as of green solvents such as deep eutectic solvents (DES) are surveyed.

Indexed as

agri-food wastesdeep eutectic solventsmicrowave assisted extractionNaviglio extractorphenolic compoundssupercritical fluid extractionsustainabilityultrasound assisted extraction

Identifiers

PMID32457916
PMCPMC7221145

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.