Evidence map›Paper›PMID 32457875›Full record

ArticleFrontiers in chemistry2020

Platelet-Membrane-Camouflaged Zirconia Nanoparticles Inhibit the Invasion and Metastasis of Hela Cells.

Yinghui Shang, Qinghai Wang, Jian Li, Qiangqiang Zhao, Xueyuan Huang, Hang Dong, Haiting Liu, Rong Gui, Xinmin Nie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Yinghui ShangDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Qinghai WangDepartment of Cardiology, the Second Hospital of Shandong University, Jinan, China.
Jian LiDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Qiangqiang ZhaoDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Xueyuan HuangDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Hang DongDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Haiting LiuDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Rong GuiDepartment of Blood Transfusion, the Third Xiangya Hospital, Central South University, Changsha, China.
Xinmin NieClinical Laboratory of the Third Xiangya Hospital, Central South University, Changsha, China.
Third Xiangya Hospital · CNCentral South University · CNSecond Hospital of Shandong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zirconia nanoparticles (ZrO2 NPs) are widely applied in the field of biomedicine. In this study, we constructed a nanoplatform of ZrO2 NPs coated with a platelet membrane (PLTm), named PLT@ZrO2. PLTm nanovesicles camouflage ZrO2 NPs, prevent nanoparticles from being cleared by macrophage, and target tumor sites. Compared to ZrO2 alone, PLT@ZrO2 is better at inhibiting the invasion and metastasis of Hela cells

Indexed as

anticancerinvasionmetastasisplatelet membranezirconia

Identifiers

PMID32457875
PMCPMC7221201
OpenAlexW3022677305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.