ArticleFrontiers in pediatrics2020
Minimally Invasive Surfactant Administration for the Treatment of Neonatal Respiratory Distress Syndrome: A Multicenter Randomized Study in China.
Open access · goldAbstract read
In one paragraph
Article in Frontiers in pediatrics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 7 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 7 pooled it
3.0field-weighted citation impact, top 7% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 7 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Safety of Less Invasive Surfactant Administration in Preterm Infants: A Meta-Analysis.Pediatric pulmonology · 2026Pooled it
- A systematic scoping review of the use of surfactant replacement therapy for respiratory distress syndrome in preterm neonates in low- and middle-income countries.Frontiers in pediatrics · 2025Pooled it
- Comparative efficacy and safety of pulmonary surfactant delivery strategies in neonatal RDS: a network meta-analysis.BMC pulmonary medicine · 2024Pooled it
- Interventions to Reduce Severe Brain Injury Risk in Preterm Neonates: A Systematic Review and Meta-analysis.JAMA network open · 2023Pooled it
- Sedation for less invasive surfactant administration in preterm infants: a systematic review and meta-analysis.Pediatric research · 2023Pooled it
- Surfactant delivery via thin catheter in preterm infants: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Surfactant therapy via thin catheter in preterm infants with or at risk of respiratory distress syndrome.The Cochrane database of systematic reviews · 2021Pooled it
- Nasal Continuous Positive Airway Pressure vs Nasal Intermittent Positive Pressure Ventilation in Preterm Infants With Respiratory Distress Syndrome: A Randomized Clinical Trial.JAMA network open · 2026Trial
- A novel double-lumen tracheal tube-assisted InSurE versus LISA in preterm infants with RDS: a multicenter randomized trial.Frontiers in pediatrics · 2026Trial
- Nasal intermittent positive pressure ventilation versus nasal continuous positive airway pressure as initial respiratory support during minimally invasive surfactant therapy in preterm infants with respiratory distress syndrome: a retrospective real-world cohort study.Translational pediatrics · 2026Article
- Which surfactant is cost-effective in Neonatal Respiratory Distress Syndrome?Cost effectiveness and resource allocation : C/E · 2026Article
- Minimally invasive surfactant administration in extremely preterm infants <28 weeks gestation with spontaneous breathing: a retrospective quality improvement study on reducing invasive ventilation burden.Frontiers in pediatrics · 2026Article
- Impact of delayed cord clamping and minimally invasive surfactant administration on outcomes in premature infants with neonatal respiratory distress syndrome at less than 30 weeks gestation: a NICU quality improvement study.Frontiers in pediatrics · 2025Article
- Tiny Lungs, Big Decisions: A Meta-Analysis Comparing Minimally Invasive Surfactant Therapy Versus Intubation-Surfactant-Extubation in Preterm Neonates With Respiratory Distress Syndrome.International journal of pediatrics · 2025Article
- Less Invasive Surfactant Administration: A Viewpoint.American journal of perinatology · 2024Review
- Clinical decision thresholds for surfactant administration in preterm infants: a systematic review and network meta-analysis.EClinicalMedicine · 2023Article
- Prevention of Chronic Morbidities in Extremely Premature Newborns with LISA-nCPAP Respiratory Therapy and Adjuvant Perinatal Strategies.Antioxidants (Basel, Switzerland) · 2023Review
- Should less invasive surfactant administration (LISA) become routine practice in US neonatal units?Pediatric research · 2023Review
- Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study.BMJ paediatrics open · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 9 institutions in 1 country.
Tongyan HanDepartment of Pediatrics, Peking University Third Hospital, Beijing, China.
Huiqiang LiuDepartment of Pediatrics, Peking University Third Hospital, Beijing, China.
Hui ZhangDepartment of Pediatrics, Peking University Third Hospital, Beijing, China.
Ming GuoDepartment of Neonatology, Fifth Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Xuefeng ZhangDepartment of Neonatology, Fifth Medical Center, General Hospital of the Chinese People's Liberation Army, Beijing, China.
Yang DuanDepartment of Neonatology, Second Hospital of Tianjin Medical University, Tianjin, China.
Fuqiang SunDepartment of Neonatology, Second Hospital of Tianjin Medical University, Tianjin, China.
Xinjian LiuDepartment of Neonatology, Hebei PetroChina Central Hospital, Langfang, China.
Xiang ZhangDepartment of Neonatology, Hebei PetroChina Central Hospital, Langfang, China.
Mingtao ZhangDepartment of Neonatology, Hebei PetroChina Central Hospital, Langfang, China.
Fang LiuDepartment of Neonatology, Bethune International Peace Hospital, Shijiazhuang, China.
Lisha BaoDepartment of Neonatology, Bethune International Peace Hospital, Shijiazhuang, China.
Min XiaoDepartment of Neonatology, Cangzhou Central Hospital of Hebei Province, Cangzhou, China.
Weili LiuDepartment of Neonatology, Cangzhou Central Hospital of Hebei Province, Cangzhou, China.
Rui JiangDepartment of Neonatology, Cangzhou Central Hospital of Hebei Province, Cangzhou, China.
Jun ZhengDepartment of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjing, China.
Xiuying TianDepartment of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjing, China.
Qi GaoDepartment of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjing, China.
Wanxian ZhangDepartment of Neonatology, Tianjin Central Hospital of Obstetrics and Gynecology, Tianjing, China.
Wei GuoDepartment of Neonatology, Xingtai People's Hospital, Xingtai, China.
Ling LiDepartment of Neonatology, Xingtai People's Hospital, Xingtai, China.
Xiaomei TongDepartment of Pediatrics, Peking University Third Hospital, Beijing, China.
Tianjin Central Hospital of Gynecology Obstetrics · CNChinese People's Liberation Army · CNPeking University · CNBethune International Peace Hospital · CNHospital of Hebei Province · CNSecond Hospital of Tianjin Medical University · CNXingtai People's Hospital · CNCangzhou Central Hospital · CNPeking University Third Hospital · CN
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
bronchopulmonary dysplasiaextremely low birth weight infantsminimally invasive surfactant administrationneonatal respiratory distress syndromepatent ductus arteriosuspreterm infants
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.