Evidence map›Paper›PMID 32457628›Full record

ReviewFrontiers in pharmacology2020

The Role of Microbiomes in Pregnant Women and Offspring: Research Progress of Recent Years.

Yao Yao, Xiaoyu Cai, Chunyan Chen, Hui Fang, Yunchun Zhao, Weidong Fei, Fengying Chen, Caihong Zheng

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Nurturing futures through the maternal microbiome.Sociology of health & illness · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Observational
  11. Review
  12. Host-gut microbiota interactions during pregnancy.Evolution, medicine, and public health · 2024
    Review
  13. Review
  14. Article
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yao YaoDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Xiaoyu CaiDepartment of Pharmacy, Hangzhou First People's Hospital, Hangzhou, China.
Chunyan ChenDepartment of Pharmacy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Hui FangDepartment of Pharmacy, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, China.
Yunchun ZhaoDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Weidong FeiDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Fengying ChenDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Caihong ZhengDepartment of Pharmacy, Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Women's Hospital, School of Medicine, Zhejiang University · CNAffiliated Hospital of Hangzhou Normal University · CNHangzhou First People's Hospital · CNSir Run Run Shaw Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy is a complicated and delicate process, the maternal body undergoes changes on hormones, immunity, and metabolism during pregnancy to support fetal development. Microbiomes in the human body mainly live in the intestine, and the human gut microbiomes are complex, which composed of more than 500 to 1500 different bacteria, archaea, fungi, and viruses. Studies have shown that these microbiomes are not only involved in the digestion and absorption of food but also indispensable in regulating host health. In recent years, there has been increasing evidence that microbiomes are important for pregnant women and fetuses. During pregnancy, there will be great changes in gut microbiomes. Regulating gut microbiomes is beneficial to the health of the mother and the fetus. In addition, many complications during pregnancy are related to gut microbiomes, such as gestational diabetes, obesity, preeclampsia, digestive disorders, and autoimmune diseases. Moreover, the microbiomes in mother's milk and vagina are closely related to the colonization of microbiomes in the early life of infants. In this review, we systematically review the role of maternal microbiomes in different gestational complications, and elucidate the function and mechanism of maternal microbiomes in the neural development and immune system of offspring. These will provide a clear knowledge framework or potential research direction for researchers in related fields.

Indexed as

complicationmechanismmicrobiomesoffspringpregnancy

Identifiers

PMID32457628
PMCPMC7225329
OpenAlexW3022971967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.