Evidence map›Paper›PMID 32457601›Full record

ArticleFrontiers in pharmacology2020

An Integrative Pharmacology-Based Analysis of Refined Qingkailing Injection Against Cerebral Ischemic Stroke: A Novel Combination of Baicalin, Geniposide, Cholic Acid, and Hyodeoxycholic Acid.

Chongyang Ma, Xueqian Wang, Tian Xu, Shuang Zhang, Shuling Liu, Changming Zhai, Zisong Wang, Jie Mu, Changxiang Li, Fafeng Cheng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 42 citations in OpenAlex.

  1. Review
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  16. Current pharmaceutical biotechnology · 2022
    Article
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  19. Neuroprotective Effect of Daidzein Extracted FromFrontiers in pharmacology · 2021
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Chongyang MaSchool of Traditional Chinese Medicine, Capital Medical University, Beijing, China.
Xueqian WangSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Tian XuSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Shuang ZhangSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Shuling LiuSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Changming ZhaiDepartment of Liver Disease, Guangdong Province Hospital of Traditional Chinese Medicine Zhuhai Branch, Zhuhai, China.
Zisong WangDepartment of Traditional Chinese Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Jie MuSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Changxiang LiSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Fafeng ChengSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Qingguo WangSchool of Traditional Chinese Medicine Department, Beijing University of Chinese Medicine, Beijing, China.
Beijing University of Chinese Medicine · CNBeijing Hospital of Traditional Chinese Medicine · CNCapital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stroke is the second leading cause of death after heart disease globally and cerebral ischemic stroke accounts for approximately 70% of all incident stroke cases. We selected four main compounds from a patent Chinese medicine, Qingkailing (QKL) injection, including baicalin from

Indexed as

Chinese medicinecombination of drugischemic strokemodern Chinese medicinenetwork pharmacologyprotein protein-interaction (PPI) networkQingkailingtopological analysis

Identifiers

PMID32457601
PMCPMC7227481
OpenAlexW3022109193

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.