Evidence map›Paper›PMID 32457378›Full record

ArticleScientific reports2020

Real-time Inference and Detection of Disruptive EEG Networks for Epileptic Seizures.

Walter Bomela, Shuo Wang, Chun-An Chou, Jr-Shin Li

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 67 citations in OpenAlex.

  1. Graph theory in paediatric epilepsy: A systematic review.Dialogues in clinical neuroscience · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Walter BomelaDepartment of Electrical and Systems Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA.
Shuo WangDepartment of Mechanical & Aerospace Engineering, University of Texas at Arlington, Arlington, TX, 76010, USA.
Chun-An ChouDepartment of Mechanical and Industrial Engineering, Northeastern University, Boston, MA, 02115, USA. ch.chou@northeastern.edu.
Jr-Shin LiDepartment of Electrical and Systems Engineering, Washington University in St. Louis, St. Louis, MO, 63130, USA. jsli@wustl.edu.
Washington University in St. Louis · USNortheastern University · USThe University of Texas at Arlington · US

Funding

Collaborative Research: Inferring Dynamic Topology to Decode and Control Spatiotemporal Structures in Complex NetworksR01GM131403 · NIGMS · WASHINGTON UNIVERSITY · PI LI, JR-SHIN · 2018 to 2021
$1.6M
NIGMS NIH HHS R01 GM131403
6 · The paper itself

Abstract

Recent studies in brain science and neurological medicine paid a particular attention to develop machine learning-based techniques for the detection and prediction of epileptic seizures with electroencephalogram (EEG). As a noninvasive monitoring method to record brain electrical activities, EEG has been widely used for capturing the underlying dynamics of disruptive neuronal responses across the brain in real-time to provide clinical guidance in support of epileptic seizure treatments in practice. In this study, we introduce a novel dynamic learning method that first infers a time-varying network constituted by multivariate EEG signals, which represents the overall dynamics of the brain network, and subsequently quantifies its topological property using graph theory. We demonstrate the efficacy of our learning method to detect relatively strong synchronization (characterized by the algebraic connectivity metric) caused by abnormal neuronal firing during a seizure onset. The computational results for a realistic scalp EEG database show a detection rate of 93.6% and a false positive rate of 0.16 per hour (FP/h); furthermore, our method observes potential pre-seizure phenomena in some cases.

Indexed as

Machine LearningBiomedical EngineeringBrainChildChild, PreschoolDiagnosis, Computer-AssistedElectroencephalographyEpilepsyFemaleHumansInfantMaleSeizures

Identifiers

PMID32457378
PMCPMC7251100
OpenAlexW3031797629

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.