Evidence map›Paper›PMID 32457340›Full record

ArticleScientific reports2020

Repression of the lysogenic P

Margit Pedersen, Jesper Tvenge Neergaard, Johan Cassias, Kim Krighaar Rasmussen, Leila Lo Leggio, Kim Sneppen, Karin Hammer, Mogens Kilstrup

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. CI:Mor interactions in the lysogeny switches ofMicrobiome research reports · 2024
    Article
  4. Article
  5. Influence ofViruses · 2022
    Article
  6. Article
  7. Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Margit PedersenUniversity of Copenhagen, Department of Biology, Copenhagen, DK2200, Denmark.
Jesper Tvenge NeergaardTechnical University of Denmark, Department of Biotechnology and Biomedicine, Lyngby, DK2800, Denmark.
Johan CassiasTechnical University of Denmark, Department of Biotechnology and Biomedicine, Lyngby, DK2800, Denmark.
Kim Krighaar RasmussenUniversity of Copenhagen, Department of Chemistry, Copenhagen, DK2200, Denmark.
Leila Lo LeggioUniversity of Copenhagen, Department of Chemistry, Copenhagen, DK2200, Denmark.ORCID http://orcid.org/0000-0002-5135-0882
Kim SneppenUniversity of Copenhagen, Center for Models of Life, Copenhagen, DK2200, Denmark.
Karin HammerTechnical University of Denmark, Department of Biotechnology and Biomedicine, Lyngby, DK2800, Denmark.
Mogens KilstrupTechnical University of Denmark, Department of Biotechnology and Biomedicine, Lyngby, DK2800, Denmark. mki@bio.dtu.dk.
Technical University of Denmark · DKUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A functional genetic switch from the lactococcal bacteriophage TP901-1, deciding which of two divergently transcribing promoters becomes most active and allows this bi-stable decision to be inherited in future generations requires a DNA region of less than 1 kb. The fragment encodes two repressors, CI and MOR, transcribed from the P

Indexed as

BacteriophagesBinding SitesDNA-Binding ProteinsDNA, ViralEnterococcusGene Expression Regulation, ViralGenome, ViralLactococcus lactisLysogenyOperator Regions, GeneticPromoter Regions, GeneticRegulatory Elements, TranscriptionalRepressor ProteinsStaphylococcusStreptococcusTrans-ActivatorsDNA-Binding ProteinsDNA, Viralphage repressor proteinsRepressor ProteinsTrans-ActivatorsViral Regulatory and Accessory Proteins

Identifiers

PMID32457340
PMCPMC7250872
OpenAlexW3032199777

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.