Evidence map›Paper›PMID 32457280›Full record

ArticleJournal of biosciences2020

MiR-222 inhibition alleviates Staphylococcal Enterotoxin B-induced inflammatory acute lung injury by targeting Foxo3.

Liang Chen, Jun Chen, Guogang Xie, Limei Zhu

Abstract read
PubMed
In one paragraph

Article in Journal of biosciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Liang ChenDepartment of Infectious Disease, Beijing Jishuitan Hospital, 4th Medical College of Peking University, Beijing, China.
Jun Chen
Guogang Xie
Limei Zhu
Jiangsu Provincial Center for Disease Control and Prevention · CNNanjing Drum Tower Hospital · CNPeking University · CNShanghai First People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) is a common acute and severe disease in clinical practice. Staphylococcal Enterotoxin B (SEB) is a superantigen that can cause inflammatory ALI. MiR-222 has been demonstrated to be upregulated in SEB-induced inflammatory ALI, but its exact roles and functions remain ill-defined. In this study, SEB exposure led to inflammatory ALI and high expression of miR-222 in model mice and lung infiltrating mononuclear cells, but the inflammatory response and high expression of miR-222 were restored in miR-222

Indexed as

Acute Lung InjuryAnimalsAntagomirsBase PairingBase SequenceBronchoalveolar Lavage FluidChemokine CCL2Disease Models, AnimalEnterotoxinsFemaleForkhead Box Protein O3Gene Expression RegulationHumansInterferon-gammaInterleukin-10Interleukin-2AntagomirsCcl2 protein, mouseChemokine CCL2enterotoxin B, staphylococcalEnterotoxinsForkhead Box Protein O3FoxO3 protein, mouseIFNG protein, mouseIL10 protein, mouseInterferon-gammaInterleukin-10Interleukin-2MicroRNAsMIRN222 microRNA, mouse

Identifiers

PMID32457280
OpenAlexW3029768820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.