Evidence map›Paper›PMID 32457154›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

The multi-faceted mechano-bactericidal mechanism of nanostructured surfaces.

Elena P Ivanova, Denver P Linklater, Marco Werner, Vladimir A Baulin, XiuMei Xu, Nandi Vrancken, Sergey Rubanov, Eric Hanssen, Jason Wandiyanto, Vi Khanh Truong and 4 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

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7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Elena P IvanovaSchool of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia; elena.ivanova@rmit.edu.au.ORCID 0000-0002-5509-8071
Denver P LinklaterSchool of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia.
Marco WernerLeibniz-Institut für Polymerforschung Dresden e.V., 01069 Dresden, Germany.ORCID 0000-0001-5433-8443
Vladimir A BaulinDepartment d'Enginyeria Quimica, Universitat Rovira i Virgili, 43007 Tarragona, Spain.ORCID 0000-0003-2086-4271
XiuMei XuInteruniversitair Micro-Electronica Centrum (IMEC), Leuven 3001, Belgium.ORCID 0000-0002-3356-8693
Nandi VranckenInteruniversitair Micro-Electronica Centrum (IMEC), Leuven 3001, Belgium.
Sergey RubanovBio21 Advanced Microscopy Facility, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3052, Australia.
Eric HanssenBio21 Advanced Microscopy Facility, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC 3052, Australia.
Jason WandiyantoSchool of Science, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Vi Khanh TruongSchool of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia.
Aaron ElbourneSchool of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia.ORCID 0000-0002-4472-4372
Shane MaclaughlinAustralian Research Council Research Hub for Australian Steel Manufacturing, Wollongong, NSW 2500, Australia.
Saulius JuodkazisSchool of Science, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia.
Russell J CrawfordSchool of Science, College of Science, Engineering and Health, RMIT University, Melbourne, VIC 3000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mechano-bactericidal activity of nanostructured surfaces has become the focus of intensive research toward the development of a new generation of antibacterial surfaces, particularly in the current era of emerging antibiotic resistance. This work demonstrates the effects of an incremental increase of nanopillar height on nanostructure-induced bacterial cell death. We propose that the mechanical lysis of bacterial cells can be influenced by the degree of elasticity and clustering of highly ordered silicon nanopillar arrays. Herein, silicon nanopillar arrays with diameter 35 nm, periodicity 90 nm and increasing heights of 220, 360, and 420 nm were fabricated using deep UV immersion lithography. Nanoarrays of 360-nm-height pillars exhibited the highest degree of bactericidal activity toward both Gram stain-negative

Indexed as

Stress, MechanicalAnti-Bacterial AgentsBacterial AdhesionElasticityNanostructuresPseudomonas aeruginosaSiliconStaphylococcus aureusAnti-Bacterial AgentsSiliconantibacterialmechano-bactericidalnanostructured surface

Identifiers

PMID32457154
PMCPMC7293705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.