Evidence map›Paper›PMID 32456631›Full record

SynthesisBMC musculoskeletal disorders2020

Complications after surgical management of proximal humeral fractures: a systematic review of event terms and definitions.

N Alispahic, S Brorson, C Bahrs, A Joeris, A Steinitz, L Audigé

Registry-linked trialAbstract readSystematic Review
In one paragraph

Synthesis in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06416618 (Surgical Versus Non-surgical Treatment of Displaced Proximal Humerus Fracture in Adults Aged 50 to 65 Years), which is not on this map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06416618 narecruitingnot on this mapstarted 2024, after this paper: background citation

Surgical Versus Non-surgical Treatment of Displaced Proximal Humerus Fracture in Adults Aged 50 to 65 Years: a Pragmatic Randomized Controlled Trial

TypeinterventionalSponsorZealand University HospitalRan2024 to 2028Enrolled60ConditionsProximal Humeral Fracture, Shoulder FracturesArmsSurgical, Non surgical
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Interventions for treating proximal humeral fractures in adults.The Cochrane database of systematic reviews · 2022
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Analysis of predictors of mortality after surgical and non-surgical management in proximal humerus fractures.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

N AlispahicDepartment of Orthopedic Surgery and Traumatology, University Hospital of Basel, Basel, Switzerland.
S BrorsonDepartment of Orthopedic Surgery, Zealand University Hospital and Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.
C BahrsDepartment of Traumatology and Reconstructive Surgery, Eberhard Karls University Tübingen, BG Trauma Center Tübingen, Tübingen, Germany.
A JoerisAO Clinical Investigation and Documentation, Dübendorf, Switzerland.
A SteinitzCrossklinik, Basel, Switzerland.
L AudigéDepartment of Orthopedic Surgery and Traumatology, University Hospital of Basel, Basel, Switzerland. laurent.audige@kws.ch.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe most frequently used surgical procedures for treating a proximal humeral fracture (PHF) are plate osteosynthesis, nail osteosynthesis and arthroplasty. Evidence-based recommendations for an appropriate surgical procedure after PHF requires transparent and valid safety data. We performed a systematic review to examine reported terms and definitions of complications after surgically-treated PHFs.

methodsA literature search was conducted on PubMed, Cochrane Library, EMBASE, Scopus and WorldCat to identify clinical articles and book chapters on complications of PHF published from 2010 to 2017. Complication terms and definitions were extracted from each selected article independently by two reviewers and grouped according to a predefined scheme.

resultsFrom 1376 initial references, we selected 470 articles, of which 103 were reviewed in reverse chronological order until no further information was gained. Twelve book chapters were reviewed. We found 667 local event terms associated with complications after surgical treatment of PHFs. The most frequently used event terms were infection (52 references), nonunion (n = 42), malunion (n = 35), avascular necrosis (n = 27) and pain (n = 25). Overall, 345, 177, 257 and 102 local event terms were related to plating, nailing, arthroplasty and other surgical techniques, respectively. Radiological assessment was the basis for the majority of event terms and complication definitions. Thirty-six event definitions were extracted, mostly defining the terms "secondary fracture displacement", "screw perforation/cutout", "malunion", "delayed healing" and "notching".

conclusionScientific literature on surgically-managed PHF uses different terms to describe complications and without approved definitions, which highlights a lack of agreement on adverse event terminology for PHFs. Defined event terms are mostly based on radiological observations. Consensus among shoulder surgeons on a core event set is indispensable to support the standardization of safety reporting for surgically-treated PHFs.

Indexed as

Arthroplasty, ReplacementDisease ManagementConsensusFracture Fixation, InternalHumansPostoperative ComplicationsShoulderShoulder FracturesTreatment OutcomeAdverse eventsComplicationsProximal humeral fracturesStandardizationSurgical treatmentSystematic literature reviewUnfavorable events

Identifiers

PMID32456631
PMCPMC7251821

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.