Evidence map›Paper›PMID 32456598›Full record

ArticleInnate immunity2020

IL-33/ST2 axis promotes the inflammatory response of nasal mucosal epithelial cells through inducing the ERK1/2 pathway.

Yun-Qiu Li, Yu Zhong, Xu-Ping Xiao, Dan-Dan Li, Zheng Zhou, Yan-Yan Tian

Open access · goldAbstract read
In one paragraph

Article in Innate immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
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  5. Bone Marrow-Derived C-KitApplied biochemistry and biotechnology · 2024
    Article
  6. Foods (Basel, Switzerland) · 2024
    Article
  7. Review
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  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yun-Qiu LiDepartment of Otolaryngology Head and Neck Surgery, Hunan Provincial People's Hospital, P.R. China.
Yu ZhongDepartment of Otolaryngology Head and Neck Surgery, Hunan Provincial People's Hospital, P.R. China.
Xu-Ping XiaoDepartment of Otolaryngology Head and Neck Surgery, Hunan Provincial People's Hospital, P.R. China.
Dan-Dan LiDepartment of Otolaryngology Head and Neck Surgery, Hunan Provincial People's Hospital, P.R. China.
Zheng ZhouDepartment of Otolaryngology Head and Neck Surgery, Hunan Provincial People's Hospital, P.R. China.
Yan-Yan TianChronic Disease Management Center of Hunan Provincial People's Hospital, P.R. China.ORCID 0000-0003-1581-355X
Hunan Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allergic rhinitis (AR) is a nasal mucosal inflammatory disease mediated by environmental allergens. At present, the relationship between the IL-33/ST2 axis, ERK1/2 pathway and AR progression needs further exploration. In our study, an AR model was constructed

Indexed as

Antigens, DermatophagoidesApoptosisArthropod ProteinsCells, CulturedCysteine EndopeptidasesCytokinesDisease ProgressionEpithelial CellsHumansInflammationInflammation MediatorsInterleukin-1 Receptor-Like 1 ProteinInterleukin-33MAP Kinase Signaling SystemNasal MucosaRhinitis, AllergicAntigens, DermatophagoidesArthropod ProteinsCysteine EndopeptidasesCytokinesDermatophagoides pteronyssinus antigen p 1IL1RL1 protein, humanInflammation MediatorsInterleukin-1 Receptor-Like 1 ProteinInterleukin-33RNA, Small InterferingAllergic rhinitisERK1/2 pathwayIL-33inflammationST2

Identifiers

PMID32456598
PMCPMC7491240
OpenAlexW3028722183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.