Evidence map›Paper›PMID 32456345›Full record

ArticleJournal of cardiovascular development and disease2020

Transforming Growth Factor Beta3 is Required for Cardiovascular Development.

Mrinmay Chakrabarti, Nadia Al-Sammarraie, Mengistu G Gebere, Aniket Bhattacharya, Sunita Chopra, John Johnson, Edsel A Peña, John F Eberth, Robert E Poelmann, Adriana C Gittenberger-de Groot and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Parallel shifts in differential gene expression reveal convergent miniaturization in fishes.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Modulation of mechanosensitive genes during embryonic aortic arch development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. The role of transforming growth factor beta in bicuspid aortic valve aortopathy.Indian journal of thoracic and cardiovascular surgery · 2023
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
  19. Endothelial-Mesenchymal Transition in Cardiovascular Disease.Arteriosclerosis, thrombosis, and vascular biology · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Mrinmay ChakrabartiDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Nadia Al-SammarraieDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Mengistu G GebereDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Aniket BhattacharyaDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Sunita ChopraDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
John JohnsonDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.
Edsel A PeñaDepartment of Statistics, University of South Carolina, Columbia, SC 290208, USA.
John F EberthDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0003-1053-9045
Robert E PoelmannDepartment of Cardiology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Adriana C Gittenberger-de GrootDepartment of Cardiology, Leiden University Medical Center, 2333 ZC Leiden, The Netherlands.
Mohamad AzharDepartment of Cell Biology and Anatomy, University of South Carolina School of Medicine, Columbia, SC 29209, USA.ORCID 0000-0001-9228-8096
University of South Carolina · USLeiden University Medical Center · NL

Funding

Analysis of TGFbeta ligands function in heart development and diseaseR01HL126705 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI AZHAR, MOHAMAD · 2015 to 2018
$1.4M
American Heart Association 17GRNT33650018NHLBI NIH HHS R01 HL126705NIH HHS R01 HL126705, R01 HL145064, R01 CA218578
6 · The paper itself

Abstract

Transforming growth factor beta3 (

Indexed as

arrhythmogenic right ventricular dysplasiacardiac developmentcleft palatecongenital heart diseaseloeys dietz syndrome-5outflow tract septationrienhoff syndromesignaling networkstransforming growth factor beta-3

Identifiers

PMID32456345
PMCPMC7344558
OpenAlexW3027718792

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.