Evidence map›Paper›PMID 32456305›Full record

ArticlePharmaceutics2020

Injectable SN-38-embedded Polymeric Microparticles Promote Antitumor Efficacy against Malignant Glioma in an Animal Model.

Yuan-Yun Tseng, Tao-Chieh Yang, Shu-Mei Chen, Shun-Tai Yang, Ya-Ling Tang, Shih-Jung Liu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Yuan-Yun TsengDivision of Neurosurgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei 11031, Taiwan.
Tao-Chieh YangDepartment of Neurosurgery, Chung Shan Medical University Hospital, Taichung 40201, Taiwan.
Shu-Mei ChenDepartment of Neurosurgery, Taipei Medical University Hospital, Taipei Medical University, Taipei 11031, Taiwan.
Shun-Tai YangDivision of Neurosurgery, Department of Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei 11031, Taiwan.
Ya-Ling TangDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, Taiwan.
Shih-Jung LiuDepartment of Mechanical Engineering, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0003-2083-4865
Chang Gung University · TWTaipei Medical University-Shuang Ho Hospital · TWChung Shan Medical University Hospital · TWTaipei Medical University Hospital · TW

Funding

Chang Gung Memorial Hospital CMRPD2K0071National Science Council NSC108-2314-B-038-060
6 · The paper itself

Abstract

Malignant glioma (MG) is extremely aggressive and highly resistant to chemotherapeutic agents. Using electrospraying, the potent chemotherapeutic agent 7-ethyl-10-hydroxycamptothecia (SN-38) was embedded into 50:50 biodegradable poly[(d,l)-lactide-

Indexed as

7-ethyl-10-hydroxycamptothecia (SN-38)intratumoral drug deliveryirinotecan (CPT-11)malignant glioma (MG)poly(lactide-co-glycolide) (PLGA)

Identifiers

PMID32456305
PMCPMC7285024
OpenAlexW3026715468

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.