Evidence map›Paper›PMID 32456132›Full record

ArticlePolymers2020

Development and Performance of Bioactive Compounds-Loaded Cellulose/Collagen/Polyurethane Materials.

Iuliana Spiridon, Narcis Anghel, Maria Valentina Dinu, Stelian Vlad, Adrian Bele, Bianca Iulia Ciubotaru, Liliana Verestiuc, Daniela Pamfil

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 40 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Iuliana Spiridon"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Narcis Anghel"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.ORCID 0000-0001-5304-0629
Maria Valentina Dinu"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Stelian Vlad"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Adrian Bele"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Bianca Iulia CiubotaruFaculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy, 9-13 Kogălniceanu Street, 700454 Iași, Romania.
Liliana VerestiucFaculty of Medical Bioengineering, Grigore T. Popa University of Medicine and Pharmacy, 9-13 Kogălniceanu Street, 700454 Iași, Romania.ORCID 0000-0002-3098-8406
Daniela Pamfil"Petru Poni" Institute of Macromolecular Chemistry, Grigore Ghica-Vodă 41, 700487 Iași, Romania.
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we present a new biomaterial based on cellulose, collagen and polyurethane, obtained by dissolving in butyl imidazole chloride. This material served as a matrix for the incorporation of tannin and lipoic acid, as well as bioactive substances with antioxidant properties. The introduction of these bioactive principles into the base matrix led to an increase of the compressive strength in the range 105-139 kPa. An increase of 29.85% of the mucoadhesiveness of the film containing tannin, as compared to the reference, prolongs the bioavailability of the active substance; a fact also demonstrated by the controlled release studies. The presence of bioactive principles, as well as tannins and lipoic acid, gives biomaterials an antioxidant capacity on average 40%-50% higher compared to the base matrix. The results of the tests of the mechanical resistance, mucoadhesiveness, bioadhesiveness, water absorption and antioxidant capacity of active principles recommend these biomaterials for the manufacture of cosmetic masks or patches.

Indexed as

biomaterialscellulosecollagenlipoic acidQuercus robur L.tannins

Identifiers

PMID32456132
PMCPMC7284988
OpenAlexW3026888429

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.