Evidence map›Paper›PMID 32456011›Full record

ReviewViruses2020

The Role of Extracellular Vesicles as Allies of HIV, HCV and SARS Viruses.

Flavia Giannessi, Alessandra Aiello, Francesca Franchi, Zulema Antonia Percario, Elisabetta Affabris

Open access · goldAbstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Liver Macrophages in the Pathogenesis of Viral Hepatitis.Current issues in molecular biology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Exosomes and SARS-CoV-2 infection.Frontiers in immunology · 2024
    Review
  16. Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Flavia GiannessiDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Alessandra AielloDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Francesca FranchiDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Zulema Antonia PercarioDepartment of Science, Roma Tre University, 00146 Rome, Italy.
Elisabetta AffabrisDepartment of Science, Roma Tre University, 00146 Rome, Italy.ORCID 0000-0001-5142-8144
Roma Tre University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are lipid bilayer-enclosed entities containing proteins and nucleic acids that mediate intercellular communication, in both physiological and pathological conditions. EVs resemble enveloped viruses in both structural and functional aspects. In full analogy with viral biogenesis, some of these vesicles are generated inside cells and, once released into the extracellular milieu, are called "exosomes". Others bud from the plasma membrane and are generally referred to as "microvesicles". In this review, we will discuss the state of the art of the current studies on the relationship between EVs and viruses and their involvement in three important viral infections caused by HIV, HCV and Severe Acute Respiratory Syndrome (SARS) viruses. HIV and HCV are two well-known pathogens that hijack EVs content and release to create a suitable environment for viral infection. SARS viruses are a new entry in the world of EVs studies, but are equally important in this historical framework. A thorough knowledge of the involvement of the EVs in viral infections could be helpful for the development of new therapeutic strategies to counteract different pathogens.

Indexed as

Cell CommunicationCoronavirusCoronavirus InfectionsExosomesExtracellular VesiclesHepacivirusHepatitis CHIV-1HIV InfectionsHumansSevere Acute Respiratory SyndromeSevere acute respiratory syndrome-related coronavirusVirus Diseasescoronavirusesexosomesextracellular vesiclesHCVHIVSARS viruses

Identifiers

PMID32456011
PMCPMC7291340
OpenAlexW3028503968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.