ArticleJournal of clinical medicine2020
Intracellular Water Content in Lean Mass as an Indicator of Muscle Quality in an Older Obese Population.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 17 citations in OpenAlex.
- Antiobesity and Hypolipidemic Potential ofNutrients · 2024Trial
- Circulating MicroRNAs Reflect Body Composition Features in Newly Diagnosed Breast Cancer.International journal of molecular sciences · 2026Article
- Intracellular Water Indexed to Height Squared as a Complementary Marker to Skeletal Muscle Index Across Nutritional and Hydration Status.Muscles (Basel, Switzerland) · 2026Article
- Indirect estimates of cellular hydration and relative water content and their associations with muscle strength and physical function in older adults: a path analysis from the Pro-Eva study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026Article
- No Ergogenic Effect of Caffeine or Sodium Bicarbonate on Resistance Exercise Performance: A Double-Blind Crossover Study with Sex-Based Analysis.Sports (Basel, Switzerland) · 2025Article
- Effect of small variations in hydration status due to 12-hour fasting on lower limb muscle function in middle-aged adults.Physical activity and nutrition · 2025Article
- Early change in lean tissue mass after peritoneal dialysis: prevalence, risk factors, and clinical implications.BMC nephrology · 2025Article
- Relationship Between Mediterranean Diet Adherence and Body Composition Parameters in Older Adults from the Mediterranean Region.Nutrients · 2024Article
- Can Functional Motor Capacity Influence Mortality in Advanced Chronic Kidney Disease Patients?Nutrients · 2024Observational
- Decreased intracellular water is associated with sarcopenic obesity in chronic haemodialysis patients.BMC geriatrics · 2023Article
- Extracellular water to total body water ratio predicts survival in cancer patients with sarcopenia: a multi-center cohort study.Nutrition & metabolism · 2022Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundIn aged populations, muscle strength depends more on muscle quality than on muscle quantity, while all three are criteria for the diagnosis of sarcopenia. Intracellular water content (ICW) in lean mass (LM) has been proposed as an indicator of muscle quality related to muscle strength in older people.
objectivesTo evaluate the relationship between the ICW/LM ratio, muscle strength and indicators of functional performance in obese older adults, and to assess the value of the ICW/LM ratio as an indicator of muscle quality. METHODOLOGY: Design: cross-sectional study. POPULATION: persons aged 65-75 years with a body mass index of 30-39 kg/m
resultsRecruited were 305 subjects (66% women), mean age 68 years. The ICW/LM ratio correlated with the TUG test, gait speed and grip strength, and was also associated with sex, the unipedal stance test and frailty. Independently of age, sex and muscle mass, the ICW/LM ratio was related with gait speed, the TUG test and unipedal stance capacity. One person (0.3%) had sarcopenia defined as low muscle strength and low muscle mass, while 25 people (8.2%) had sarcopenia defined as low muscle strength and poor muscle quality (ICW/LM). With this last definition, sarcopenia was related to frailty, gait speed and the TUG test.
conclusionsICW content in LM could be a useful muscle quality indicator for defining sarcopenia. However, more studies are required to confirm our findings for other populations.
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