Evidence map›Paper›PMID 32455959›Full record

ArticleInternational journal of molecular sciences2020

Delayed NK Cell Reconstitution and Reduced NK Activity Increased the Risks of CMV Disease in Allogeneic-Hematopoietic Stem Cell Transplantation.

Ki Hyun Park, Ji Hyeong Ryu, Hyunjoo Bae, Sojeong Yun, Joo Hee Jang, Kyungja Han, Byung Sik Cho, Hee-Je Kim, Hyeyoung Lee, Eun-Jee Oh

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Ki Hyun ParkDepartment of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Ji Hyeong RyuDepartment of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Hyunjoo BaeDepartment of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Sojeong YunDepartment of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Joo Hee JangDepartment of Biomedicine & Health Sciences, Graduate School, The Catholic University of Korea, Seoul 06591, Korea.
Kyungja HanDepartment of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Byung Sik ChoDepartment of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.
Hee-Je KimDepartment of Hematology, Catholic Hematology Hospital, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0003-4098-3366
Hyeyoung LeeDepartment of Laboratory Medicine, Catholic Kwandong University International St. Mary's Hospital, Incheon 22711, Korea. shomermaid@catholic.ac.kr.
Eun-Jee OhDepartment of Laboratory Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 06591, Korea.ORCID 0000-0001-5870-915X
The Catholic University of Korea Seoul St. Mary's Hospital · KRCatholic University of Korea · KRCatholic Kwandong University International St. Mary's Hospital · KR

Funding

National Research Foundation of Korea NRF-2017R1A2B4011181
6 · The paper itself

Abstract

Cytomegalovirus (CMV) infection has a significant impact in patients after allogeneic hematopoietic stem cell transplantation (HSCT). We investigated natural killer (NK) cell reconstitution and cytotoxic/cytokine production in controlling CMV infection, especially severe CMV disease in HSCT patients. Fifty-eight patients with acute myeloid leukemia (AML) who received allo-HSCT were included. We monitored NK reconstitution and NK function at baseline, 30, 60, 90, 120, 150, and 180 days after HSCT, and compared the results in recipients stratified on post-HSCT CMV reactivation (

Indexed as

Hematopoietic Stem Cell TransplantationAdolescentAdultAgedCell Line, TumorCytomegalovirusCytomegalovirus InfectionsFemaleHumansImmunophenotypingInterferon-gammaKiller Cells, NaturalLeukemia, Myeloid, AcuteMaleMiddle AgedReceptors, Natural Killer CellInterferon-gammaReceptors, Natural Killer Cellacute myeloid leukemiacytomegalovirushematopoietic stem cell transplantationIFNγNK cell-mediated antibody-dependent cellular cytotoxicityNK cellsNK subsets

Identifiers

PMID32455959
PMCPMC7279475
OpenAlexW3027690889

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.