Evidence map›Paper›PMID 32455885›Full record

ReviewCells2020

From Tank to Treatment: Modeling Melanoma in Zebrafish.

William Tyler Frantz, Craig J Ceol

Abstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Long-term imaging of living adult zebrafish.Development (Cambridge, England) · 2022
    Article
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Deciphering Melanoma Cell States and Plasticity with Zebrafish Models.The Journal of investigative dermatology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

William Tyler FrantzProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Craig J CeolProgram in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Funding

Translational Cancer Biology Training ProgramT32CA130807 · NCI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI MERCURIO, ARTHUR M · 2008 to 2018
$2.7M
NCI NIH HHS T32 CA130807
6 · The paper itself

Abstract

Melanoma is the deadliest form of skin cancer and one of few cancers with a growing incidence. A thorough understanding of its pathogenesis is fundamental to developing new strategies to combat mortality and morbidity. Zebrafish-due in large part to their tractable genetics, conserved pathways, and optical properties-have emerged as an excellent system to model melanoma. Zebrafish have been used to study melanoma from a single tumor initiating cell, through metastasis, remission, and finally into relapse. In this review, we examine seminal zebrafish studies that have advanced our understanding of melanoma.

Indexed as

AnimalsDisease Models, AnimalGenetic Predisposition to DiseaseMelanocytesMelanomaNeural CrestZebrafishgeneticsmelanocytesMelanomamicroenvironmentmodelingxenograftszebrafish

Identifiers

PMID32455885
PMCPMC7290816

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.