ArticleJournal of clinical medicine2020
Timing of Transfusion, not Hemoglobin Variability, is Associated with 3-Month Outcomes in Acute Ischemic Stroke.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Volume of red blood cell transfusion is a risk factor for acute ischemic stroke after non-variceal upper gastrointestinal bleeding.Frontiers in neurology · 2025Article
- Anemia Is a Risk Factor for the Development of Ischemic Stroke and Post-Stroke Mortality.Journal of clinical medicine · 2021Article
- Updates in Stroke Treatment, Diagnostic Methods and Predictors of Outcome.Journal of clinical medicine · 2020Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
methodsWe studied consecutive patients with AIS admitted in three tertiary hospitals who received red blood cell (RBC) transfusion (RBCT) during admission. Hemoglobin variability was assessed by minimum, maximum, range, median absolute deviation, and mean absolute change in hemoglobin level. Timing of RBCT was grouped into two categories: admission to 48 h (early) or more than 48 h (late) after hospitalization. Late RBCT was entered into multivariable logistic regression model. Poor outcome at three months was defined as a modified Rankin Scale score ≥3.
resultsOf 2698 patients, 132 patients (4.9%) received a median of 400 mL (interquartile range: 400-840 mL) of packed RBCs. One-hundred-and-two patients (77.3%) had poor outcomes. The most common cause of RBCT was gastrointestinal bleeding (27.3%). The type of anemia was not associated with the timing of RBCT. Late RBCT was associated with poor outcome (odd ratio (OR), 3.55; 95% confidence interval (CI), 1.43-8.79;
conclusionLate RBCT, rather than hemoglobin variability indices, is a predictor for poor outcome in patients with AIS.
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