Evidence map›Paper›PMID 32455829›Full record

ArticleCancers2020

Relapse-Free Survival and PD-L1 Expression in First High- and Low-Grade Relapsed Luminal, Basal and Double-Negative P53-Mutant Non-Muscular Invasive Bladder Cancer Depending on Previous Chemo- and Immunotherapy.

Ekaterina Blinova, Dmitry Enikeev, Dmitry Roshchin, Elena Samyshina, Olga Deryabina, Aleksander Tertychnyy, Dmitry Blinov, Evgenia Kogan, Marina Dudina, Haydar Barakat and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Prognostic Role ofLife (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Ekaterina BlinovaDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Dmitry EnikeevDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Dmitry RoshchinDepartment of Oncological Urology, Russian National Research Center of Radiology, 3 2nd Botkinsky Proezd, 125284 Moscow, Russia.
Elena SamyshinaLaboratory of Molecular Pharmacology and Drug Design, All-Union Research Center for Biological Active Compounds Safety, 23 Kirova Street, 142450 Staraja Kupavna, Russia.
Olga DeryabinaDepartment of Oncology, Laboratory of Pharmacology, National Research Ogarev Mordovia State University, 68 Bolshevistskaya Street, 430005 Saransk, Russia.
Aleksander TertychnyyDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Dmitry BlinovLaboratory of Molecular Pharmacology and Drug Design, All-Union Research Center for Biological Active Compounds Safety, 23 Kirova Street, 142450 Staraja Kupavna, Russia.ORCID 0000-0002-8385-4356
Evgenia KoganDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Marina DudinaDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Haydar BarakatDepartment of Bioinformatics, People's Friendship University of Russia, 6 Miklukho-Maklaya Street, 117198 Moscow, Russia.
Dmitrij MerinovDepartment of Oncological Urology, Russian National Research Center of Radiology, 3 2nd Botkinsky Proezd, 125284 Moscow, Russia.
Aleksandr KachmazovDepartment of Oncological Urology, Russian National Research Center of Radiology, 3 2nd Botkinsky Proezd, 125284 Moscow, Russia.
Stanislav SerebrianyiDepartment of Oncological Urology, Russian National Research Center of Radiology, 3 2nd Botkinsky Proezd, 125284 Moscow, Russia.
Natalia PotoldykovaDepartment of Clinical Anatomy and Operative Surgery, Department of Pathological Anatomy, Institute for Urology and Reproductive Health, Sechenov University, 8/1 Trubetzkaya Street, 119991 Moscow, Russia.
Dmitrij PerepechinDepartment of Oncological Urology, Russian National Research Center of Radiology, 3 2nd Botkinsky Proezd, 125284 Moscow, Russia.
Sechenov University · RUNational Research Mordovia State University · RUPeoples' Friendship University of Russia · RU

Funding

Russian academic excellence project "5-100" for Sechenov First Moscow State Medical University 5-100
6 · The paper itself

Abstract

The goal of this study was to assess how PD-L1 expression in tissue specimens of patients with main molecular subtypes of NMIBC (luminal, basal and double-negative p53-mutant) associates with relapsed-free survival in dependence on the tumor grade and prior treatment of primary bladder cancer. PD-L1 expressions on the membrane of neoplastic and CD8+ immune cells were assessed in tumor specimens (

Indexed as

immune cellsmalignant cellsmolecular subtypenon-muscular invasive bladder cancerPD-L1 expressionrelapsesurvivaltumor grade

Identifiers

PMID32455829
PMCPMC7281187
OpenAlexW3028551736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.