Evidence map›Paper›PMID 32455784›Full record

ArticleAntibiotics (Basel, Switzerland)2020

Isolation, Characterization and Chemical Synthesis of Large Spectrum Antimicrobial Cyclic Dipeptide (l-leu-l-pro) from

Ilhem Saadouli, Imène Zendah El Euch, Emna Trabelsi, Amor Mosbah, Alaeddine Redissi, Raoudha Ferjani, Imene Fhoula, Ameur Cherif, Jean-Marc Sabatier, Norbert Sewald and 1 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Peptide-Based Materials That Exploit Metal Coordination.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Review
  14. Recently Discovered Secondary Metabolites fromMolecules (Basel, Switzerland) · 2022
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ilhem SaadouliLR03ES03, Laboratoire de Microorganismes et Biomolécules Actives, Faculté des Sciences de Tunis, Université Tunis Manar, Tunis 2092, Tunisia.
Imène Zendah El EuchLR03ES03, Laboratoire de Microorganismes et Biomolécules Actives, Faculté des Sciences de Tunis, Université Tunis Manar, Tunis 2092, Tunisia.
Emna TrabelsiHigher Institute for Biotechnology (ISBST), LR Biotechnology and Bio-Geo Resources Valorization, University of Manouba,BVBGR-LR11ES31, BiotechpoleSidiThabet, Ariana 2020, Tunisia.
Amor MosbahHigher Institute for Biotechnology (ISBST), LR Biotechnology and Bio-Geo Resources Valorization, University of Manouba,BVBGR-LR11ES31, BiotechpoleSidiThabet, Ariana 2020, Tunisia.
Alaeddine RedissiHigher Institute for Biotechnology (ISBST), LR Biotechnology and Bio-Geo Resources Valorization, University of Manouba,BVBGR-LR11ES31, BiotechpoleSidiThabet, Ariana 2020, Tunisia.
Raoudha FerjaniLR03ES03, Laboratoire de Microorganismes et Biomolécules Actives, Faculté des Sciences de Tunis, Université Tunis Manar, Tunis 2092, Tunisia.
Imene FhoulaLR03ES03, Laboratoire de Microorganismes et Biomolécules Actives, Faculté des Sciences de Tunis, Université Tunis Manar, Tunis 2092, Tunisia.
Ameur CherifHigher Institute for Biotechnology (ISBST), LR Biotechnology and Bio-Geo Resources Valorization, University of Manouba,BVBGR-LR11ES31, BiotechpoleSidiThabet, Ariana 2020, Tunisia.
Jean-Marc SabatierInstitute of Neuro Physiopathology (INP), Université d'Aix-Marseille, UMR 7051, Faculté de Pharmacie, 27 Bd Jean Moulin, 13385 Marseille CEDEX, France.
Norbert SewaldOrganic and Bioorganic Chemistry, Department of Chemistry, Bielefeld University, Universitätsstraße 25, 33615 Bielefeld, Germany.
Hadda-Imene OuzariLR03ES03, Laboratoire de Microorganismes et Biomolécules Actives, Faculté des Sciences de Tunis, Université Tunis Manar, Tunis 2092, Tunisia.

Funding

German Academic Exchange Service (DAAD) ID57166072The Tunisian Ministry of Higher Education and Scientific Research LR03ES03
6 · The paper itself

Abstract

Streptomyces is the most frequently described genus of Actinomycetes, a producer of biologically active secondary metabolites. Indeed, the Streptomyces species produces about 70% of antibiotics and 60% of antifungal molecules used in agriculture. Our study was carried out with the goal of isolating and identifying antimicrobial secondary metabolites from

Indexed as

antimicrobial activitycyclic dipeptide (l-Leucyl-l-Proline)Keywords Streptomyces misionensis

Identifiers

PMID32455784
PMCPMC7277807

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.