Evidence map›Paper›PMID 32455724›Full record

ArticleNutrients2020

Mulberry Fruit Extract Promotes Serum HDL-Cholesterol Levels and Suppresses Hepatic microRNA-33 Expression in Rats Fed High Cholesterol/Cholic Acid Diet.

Soojin Lee, Mak-Soon Lee, Eugene Chang, Yoonjin Lee, Jaerin Lee, Jiyeon Kim, Chong-Tai Kim, In-Hwan Kim, Yangha Kim

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 30 citations in OpenAlex.

  1. Effect of encapsulatedVeterinary and animal science · 2025
    Article
  2. Review
  3. Micro-Executor of Natural Products in Metabolic Diseases.Molecules (Basel, Switzerland) · 2023
    Review
  4. Review
  5. Article
  6. Nutrients · 2022
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Soojin LeeDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Mak-Soon LeeDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Eugene ChangDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Yoonjin LeeDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Jaerin LeeDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Jiyeon KimDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Chong-Tai KimR&D Center, EastHill Corporation, Gwonseon-gu, Suwon-si, Gyeonggi-do 16642, Korea.
In-Hwan KimDepartment of Integrated Biomedical and Life Sciences, Korea University, Seoul 02841, Korea.
Yangha KimDepartment of Nutritional Science and Food Management, Ewha Womans University, Seoul 03760, Korea.
Ewha Womans University · KRKorea University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum high-density lipoprotein cholesterol (HDL-C) levels and cholesterol excretion are closely associated with the risk of cardiovascular complications. The specific aim of the present study was to investigate the cholesterol lowering effect of mulberry fruit in rats fed a high cholesterol/cholic acid diet. Four-week supplementation with mulberry fruit extract significantly decreased serum and hepatic cholesterol (TC), serum low-density lipoprotein cholesterol (LDL-C), and fecal bile acid levels without changes in body weight and food intake (

Indexed as

AnimalsATP Binding Cassette Transporter, Subfamily G, Member 5Bile Acids and SaltsCholesterolCholesterol 7-alpha-HydroxylaseCholesterol, HDLCholic AcidDisease Models, AnimalFruitGene Expression RegulationHypercholesterolemiaLipoproteinsLipoproteins, LDLLiverLiver X ReceptorsMaleAbcg5 protein, ratATP Binding Cassette Transporter, Subfamily G, Member 5Bile Acids and SaltsCholesterolCholesterol 7-alpha-HydroxylaseCholesterol, HDLCholic AcidCYP7A1 protein, ratLipoproteinsLipoproteins, LDLLiver X ReceptorsMicroRNAsMIRN33 microRNA, ratPlant ExtractsRNA, MessengerSterol Regulatory Element Binding Protein 2bile acidcholesterol effluxhigh-density lipoprotein cholesterol (HDL-C)microRNA-33mulberry fruit

Identifiers

PMID32455724
PMCPMC7284868
OpenAlexW3027212635

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.