Evidence map›Paper›PMID 32455577›Full record

ArticleCancers2020

HuRdling Senescence: HuR Breaks BRAF-Induced Senescence in Melanocytes and Supports Melanoma Growth.

Janika K Liebig, Silke Kuphal, Anja Katrin Bosserhoff

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
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  8. PredictingJournal of skin cancer · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Janika K LiebigInstitute of Biochemistry, Emil-Fischer Zentrum, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Silke KuphalInstitute of Biochemistry, Emil-Fischer Zentrum, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.
Anja Katrin BosserhoffInstitute of Biochemistry, Emil-Fischer Zentrum, Friedrich-Alexander University of Erlangen-Nürnberg (FAU), 91054 Erlangen, Germany.ORCID 0000-0001-8147-394X
Friedrich-Alexander-Universität Erlangen-Nürnberg · DE

Funding

Deutsche Forschungsgemeinschaft BO1573IZKF Erlangen D31Wilhelm Sander-Stiftung AB
6 · The paper itself

Abstract

In addition to genetic changes, post-transcriptional events strongly contribute to the progression of malignant tumors. The RNA-binding protein HuR (

Indexed as

HuRmalignant melanomaMicrophthalmia-associated transcription factorMITFoncogene induced senescence

Identifiers

PMID32455577
PMCPMC7281285
OpenAlexW3026059723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.