ArticlePharmaceutics2020
Wound Healing Activity of Nanoclay/Spring Water Hydrogels.
Article in Pharmaceutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed, 42 citations in OpenAlex.
- Antibacterial bionanocomposite hydrogel based on hydroxyethyl cellulose, poly(vinyl alcohol), and montmorillonite clay as a scaffold for bone tissue engineering application.Scientific reports · 2025Article
- Preparation and characterization of tadalafil-loaded hydrogel: AnPharmaceutical science advances · 2025Article
- Influence of biopolymer based gold nanoparticles and photobiomodulation in in vitro wound healing.Scientific reports · 2025Article
- Natural Nano-Minerals (NNMs): Conception, Classification and Their Biomedical Composites.ACS omega · 2024Review
- Article
- Mycelium-based biomaterials as smart devices for skin wound healing.Frontiers in bioengineering and biotechnology · 2023Article
- Engineered Nanoparticles, Natural Nanoclay and Biochar, as Carriers of Plant-Growth Promoting Bacteria.Nanomaterials (Basel, Switzerland) · 2022Article
- Clay-Based Nanocomposite Hydrogels for Biomedical Applications: A Review.Nanomaterials (Basel, Switzerland) · 2022Review
- Clay-Based Pharmaceutical Formulations and Drug Delivery Systems.Pharmaceutics · 2020Article
- Correlation between Elemental Composition/Mobility and Skin Cell Proliferation of Fibrous Nanoclay/Spring Water Hydrogels.Pharmaceutics · 2020Article
- Nanotechnology-Based Medical Devices for the Treatment of Chronic Skin Lesions: From Research to the Clinic.Pharmaceutics · 2020Review
- Safety of Nanoclay/Spring Water Hydrogels: Assessment and Mobility of Hazardous Elements.Pharmaceutics · 2020Article
- Self-Therapeutic Nanomaterials: Applications in Biology and Medicine.Materials today (Kidlington, England)Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundhydrogels prepared with natural inorganic excipients and spring waters are commonly used in medical hydrology. Design of these clay-based formulations continues to be a field scarcely addressed. Safety and wound healing properties of different fibrous nanoclay/spring water hydrogels were addressed.
methodsin vitro biocompatibility, by means of MTT assay, and wound healing properties were studied. Confocal Laser Scanning Microscopy was used to study the morphology of fibroblasts during the wound healing process.
resultsall the ingredients demonstrated to be biocompatible towards fibroblasts. Particularly, the formulation of nanoclays as hydrogels improved biocompatibility with respect to powder samples at the same concentration. Spring waters and hydrogels were even able to promote in vitro fibroblasts motility and, therefore, accelerate wound healing with respect to the control.
conclusionfibrous nanoclay/spring water hydrogels proved to be skin-biocompatible and to possess a high potential as wound healing formulations. Moreover, these results open new prospects for these ingredients to be used in new therapeutic or cosmetic formulations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.