Evidence map›Paper›PMID 32455225›Full record

ArticleACS omega2020

Total Synthesis of Naturally Occurring 5,7,8-Trioxygenated Homoisoflavonoids.

Sangil Kwon, Sanha Lee, Myunghoe Heo, Bit Lee, Xiang Fei, Timothy W Corson, Seung-Yong Seo

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Gastroprotective effects ofSaudi journal of biological sciences · 2023
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Sangil KwonCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Sanha LeeCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Myunghoe HeoCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Bit LeeCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Xiang FeiCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Timothy W CorsonEugene and Marilyn Glick Eye Institute, Department of Ophthalmology, Department of Biochemistry and Molecular Biology, Department of Pharmacology and Toxicology, and Melvin and Bren Simon Cancer Center, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States.
Seung-Yong SeoCollege of Pharmacy, Gachon University, Incheon 21936, Republic of Korea.
Gachon University · KRIndiana University Health · US

Funding

Ferrochelatase as a mediator of ocular angiogenesisR01EY025641 · NEI · UNIVERSITY OF TORONTO · PI Timothy W Corson · 2016 to 2026
$3.5M
NEI NIH HHS R01 EY025641
6 · The paper itself

Abstract

Homoisoflavonoids are in the subclass of the larger family of flavonoids but have one more alkyl carbon than flavonoids. Among them, 5,7,8-trioxygenated homoisoflavonoids have not been extensively studied for synthesis and biological evaluation. Our current objective is to synthesize 2 5,7,8-trioxygenated chroman-4-ones and 12 5,7,8-trioxygenated homoisoflavonoids that have been isolated from the plants

Identifiers

PMID32455225
PMCPMC7241036
OpenAlexW3022020487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.