Evidence map›Paper›PMID 32455176›Full record

ArticleHeliyon2020

Cytotoxic effect of selected wild orchids on two different human cancer cell lines.

Pusp Raj Joshi, Mukti Ram Paudel, Mukesh Babu Chand, Shreeti Pradhan, Krishna Kumar Pant, Giri Prasad Joshi, Manoj Bohara, Sven H Wagner, Basant Pant, Bijaya Pant

Abstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. 1,5,6-Trimethoxy-2,7-dihydroxyphenanthrene fromInternational journal of molecular sciences · 2023
    Article
  3. Article
  4. Article
  5. Review
  6. Dihydrophenanthrenes from a Sicilian Accession ofPlants (Basel, Switzerland) · 2021
    Article
  7. Comparative Cytotoxic Activity of Wild Harvested Stems andAdvances in pharmacological and pharmaceutical sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pusp Raj JoshiCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Mukti Ram PaudelCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Mukesh Babu ChandFujian Agriculture and Forestry University, Fujian, China.
Shreeti PradhanCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Krishna Kumar PantCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Giri Prasad JoshiCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.
Manoj BoharaAnnapurna Research Center, Maitighar, Kathmandu, Nepal.
Sven H WagnerSails-For-Science Foundation, Germany.
Basant PantAnnapurna Research Center, Maitighar, Kathmandu, Nepal.
Bijaya PantCentral Department of Botany, Tribhuvan University, Kirtipur, Kathmandu, Nepal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Majority of the orchid species are used in the traditional medicines for the treatment of several diseases. They are the sources of polysaccharides, phenanthrenes, bibenzyl derivatives, revesteral, stilbenoids and polyphenol compounds. This study explored the cytotoxic activity of seven wild orchid species and identification of medicinally active compounds. The extracts of orchid species were screened for cytotoxic effect on the human cervical cancer cells (HeLa) and human glioblastoma cells (U251) using an MTT assay. The medicinally active compounds of high cytotoxic extracts were identified by GC-MS resulting in many stilbenoids and phenolic derivatives. The extract of

Indexed as

Bioactive compoundsBioactive plant productBiological sciencesBotanyGC-MSMTT assayNatural productOrchidsPharmaceutical sciencePlant biology

Identifiers

PMID32455176
PMCPMC7235618

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.