Evidence map›Paper›PMID 32455145›Full record

ReviewOpen forum infectious diseases2020

The HIV Outpatient Study-25 Years of HIV Patient Care and Epidemiologic Research.

Kate Buchacz, Carl Armon, Frank J Palella, Richard M Novak, Jack Fuhrer, Ellen Tedaldi, Douglas Ward, Cynthia Mayer, Linda Battalora, Kimberly Carlson and 4 more

Abstract readReview
In one paragraph

Review in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Review
  3. Evolving Disease Spectrum and Characteristics of People with HIV in Eastern China: A 12-Year Study.Mediterranean journal of hematology and infectious diseases · 2025
    Article
  4. Article
  5. Article
  6. Emerging from the shadows: Trends in HIV ambulatory care, viral load testing, and viral suppression in a U.S. HIV cohort, 2019-2022: Impact of COVID-19 pandemic.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2024
    Article
  7. Article
  8. Long-term Outcomes of Patients With HIV andOpen forum infectious diseases · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Kate BuchaczDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Carl ArmonCerner Corporation, Kansas City, Missouri, USA.
Frank J PalellaNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Richard M NovakUniversity of Illinois College of Medicine, Chicago, Illinois, USA.
Jack FuhrerRenaissance School of Medicine at Stony Brook University, Stony Brook, New York, USA.
Ellen TedaldiLewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.
Douglas WardDupont Circle Physicians Group, Washington, DC, USA.
Cynthia MayerSt. Joseph's Hospital Comprehensive Research Institute, Tampa Florida, USA.
Linda BattaloraCerner Corporation, Kansas City, Missouri, USA.
Kimberly CarlsonCerner Corporation, Kansas City, Missouri, USA.
Stacey PurintonCerner Corporation, Kansas City, Missouri, USA.
Marcus DurhamDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
Jun LiDivision of HIV/AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
HIV Outpatient Study (HOPS) Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The clinical epidemiology of treated HIV infection in the United States has dramatically changed in the past 25 years. Few sources of longitudinal data exist for people with HIV (PWH) spanning that period. Cohort data enable investigating new exposure and disease associations and monitoring progress along the HIV care continuum. Methods: We synthesized key published findings and conducted primary data analyses in the HIV Outpatient Study (HOPS), an open cohort of PWH seen at public and private HIV clinics since 1993. We assessed temporal trends in health outcomes (1993-2017) and mortality (1994-2017) for 10 566 HOPS participants. Results: The HOPS contributed to characterizing new conditions (eg, lipodystrophy), demonstrated reduced mortality with earlier HIV treatment, uncovered associations between select antiretroviral agents and cardiovascular disease, and documented remarkable shifts in morbidity from AIDS opportunistic infections to chronic noncommunicable diseases. The median CD4 cell count of participants increased from 244 cells/mm Conclusions: Since 1993, the HOPS has been detecting emerging issues and challenges in HIV disease management. HOPS data can also be used for monitoring trends in infectious and chronic diseases, immunologic and viral suppression status, retention in care, and survival, thereby informing progress toward the Ending the HIV Epidemic initiative.

Indexed as

antiretroviral therapyclinical outcomesHIV epidemiologyviral suppression

Identifiers

PMID32455145
PMCPMC7235508

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.