Evidence map›Paper›PMID 32454946›Full record

ArticleOxidative medicine and cellular longevity2020

Nitric Oxide Stimulates Acute Pancreatitis Pain via Activating the NF-

Mengwen Xue, Liang Han, Weikun Qian, Jie Li, Tao Qin, Ying Xiao, Qingyong Ma, Jiguang Ma, Xin Shen

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Mengwen XueDepartment of Anesthesiology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-1196-4951
Liang HanDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-3268-5214
Weikun QianDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-8389-5289
Jie LiDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.
Tao QinDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-4568-638X
Ying XiaoDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-6855-0207
Qingyong MaDepartment of Hepatobiliary Surgery, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0001-8977-320X
Jiguang MaDepartment of Anesthesiology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0002-6242-6248
Xin ShenDepartment of Anesthesiology, The First Affiliated Hospital, Xi'an Jiaotong University, Xi'an 710061, China.ORCID https://orcid.org/0000-0003-4255-5883
First Affiliated Hospital of Xi'an Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pain is the most important clinical feature of acute pancreatitis (AP); however, its specific mechanism is currently unclear. In this study, we showed that AP caused an increase in nitric oxide (NO) secretion, activated the NF-

Indexed as

Signal TransductionAnimalsAnimals, NewbornBehavior, AnimalCalcitonin Gene-Related PeptideMaleMice, Inbred C57BLNF-kappa BNitric OxideNitric Oxide Synthase Type IIPainPancreatitisRatsReceptors, Opioid, kappaSubstance PCalcitonin Gene-Related PeptideNF-kappa BNitric OxideNitric Oxide Synthase Type IIReceptors, Opioid, kappaSubstance P

Identifiers

PMID32454946
PMCPMC7231422
OpenAlexW3022380418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.