Evidence map›Paper›PMID 32454925›Full record

ArticleBiomicrofluidics2020

Closed-loop feedback control of microbubble diameter from a flow-focusing microfluidic device.

Yanjun Xie, Adam J Dixon, J M Robert Rickel, Alexander L Klibanov, John A Hossack

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomicrofluidics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yanjun XieDepartment of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA.
Adam J DixonDepartment of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA.ORCID 0000-0002-9803-2726
J M Robert RickelDepartment of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA.ORCID 0000-0002-4185-3689
Alexander L KlibanovDepartment of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA.
John A HossackDepartment of Biomedical Engineering, University of Virginia, Charlottesville 22908, USA.ORCID 0000-0003-1299-0745
University of Virginia · US

Funding

Accelerated Low Dose Thrombolytic Catheter Directed SonothrombolysisR01HL141752 · NHLBI · UNIVERSITY OF VIRGINIA · PI HOSSACK, JOHN A · 2018 to 2021
$2.0M
PiV Ultra 12 - 24 Ultra High Speed Camera for Ultrasound Microbubble ResearchS10RR025594 · NCRR · UNIVERSITY OF VIRGINIA · PI HOSSACK, JOHN A · 2009 to 2009
$499k
NCRR NIH HHS S10 RR025594NHLBI NIH HHS R01 HL141752
6 · The paper itself

Abstract

Real-time observation and control of particle size and production rate in microfluidic devices are important capabilities for a number of applications, including the production, sorting, and manipulation of microbubbles and droplets. The production of microbubbles from flow-focusing microfluidic devices had been investigated in multiple studies, but each lacked an approach for on-chip measurement and control of microbubble diameter in real time. In this work, we implement a closed-loop feedback control system in a flow-focusing microfluidic device with integrated on-chip electrodes. Using our system, we measure and count microbubbles between 13 and 28

Identifiers

PMID32454925
PMCPMC7211089
OpenAlexW3022461256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.