Evidence map›Paper›PMID 32454909›Full record

SynthesisDisease markers2020

Diagnostic Value of Neutrophil-Lymphocyte Ratio for Predicting the Severity of Acute Pancreatitis: A Meta-Analysis.

Weihao Kong, Yuanyuan He, Huarui Bao, Wenlong Zhang, Xingyu Wang

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Neutrophil-Lymphocyte Ratio and LDH/Albumin Ratio as Biomarkers for Severity and Mortality in Acute Pancreatitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Weihao KongDepartment of Emergency Surgery, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Heifei, China.ORCID https://orcid.org/0000-0002-0047-9811
Yuanyuan HeDepartment of Emergency Internal Medicine, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Heifei, China.ORCID https://orcid.org/0000-0003-1804-0302
Huarui BaoDepartment of Emergency Internal Medicine, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Heifei, China.ORCID https://orcid.org/0000-0002-8313-7787
Wenlong ZhangDepartment of Emergency Surgery, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Heifei, China.ORCID https://orcid.org/0000-0003-3584-5698
Xingyu WangDepartment of Emergency Surgery, Department of Emergency Medicine, The First Affiliated Hospital of Anhui Medical University, Heifei, China.ORCID https://orcid.org/0000-0003-1724-9892

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute pancreatitis (AP) is a life-threatening disease caused by a variety of factors, and once it progresses to severe acute pancreatitis, the prognosis is poor. The purpose of this study was to investigate the diagnostic value of the neutrophil-lymphocyte ratio (NLR) for predicting the severity of acute pancreatitis. MATERIALS AND

methodsWe searched the databases of PubMed, EMBASE, Web of Science, and Cochrane Library to identify eligible studies using the NLR to predict the severity of AP. The sensitivity (SEN), specificity (SPE), negative likelihood ratio (NLR), positive likelihood ratio (PLR), diagnostic odds ratio (DOR), and area under the receiver operating characteristic curve (AUC) were combined using a bivariate mixed model.

resultsA total of 10 articles containing 394 cases and 1319 controls were included in the study. The combined SEN, SPE, NLR, PLR, DOR, and AUC are 79% (73%-84%), 71% (59%-80%), 0.30 (0.21-0.41), 2.7 (1.8-4.0), 9 (5-18), and 0.82 (0.78-0.85), respectively.

conclusionsNLR has a moderately high diagnostic value in predicting the severity of acute pancreatitis.

Indexed as

Area Under CurveCase-Control StudiesHumansLeukocyte CountLymphocytesNeutrophilsPancreatitisPrognosisROC CurveSensitivity and SpecificitySeverity of Illness Index

Identifiers

PMID32454909
PMCPMC7232731

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.