Evidence map›Paper›PMID 32454845›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2019

Intervention Mechanisms of Xinmailong Injection, a

Shan-Shan Lin, Chun-Xiang Liu, Xian-Liang Wang, Jing-Yuan Mao

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Biology · 2025
    Article
  2. Review
  3. Article
  4. Investigation of the effects ofFrontiers in pharmacology · 2024
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Shan-Shan LinCardiovascular Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China.ORCID https://orcid.org/0000-0002-0702-6540
Chun-Xiang LiuEvidence-Based Medicine Center, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China.ORCID https://orcid.org/0000-0003-4063-3729
Xian-Liang WangCardiovascular Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China.ORCID https://orcid.org/0000-0001-6160-5650
Jing-Yuan MaoCardiovascular Department, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China.ORCID https://orcid.org/0000-0002-9882-7406
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine · CNTianjin University of Traditional Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAt present, the prevention and treatment of cardiovascular disease in the world are facing severe challenges. Xinmailong injection, which is derived from the animal medicine

methodsBasic research reports on the intervention mechanisms of Xinmailong Injection on cardiovascular disease in PubMed, EMBASE, Cochrane Library (No. 2, 2019), CNKI, Wan Fang, and VIP databases were searched. The search time limit was from the establishment of the database to February 2019. The literature was screened according to inclusion and exclusion criteria, and then the data were extracted and a descriptive analysis of the pharmacological mechanisms of Xinmailong Injection on cardiovascular disease was performed.

resultsFinally, twenty-two basic research reports were included. The intervention mechanisms of Xinmailong Injection on cardiovascular disease mainly includes the following: inhibiting oxidative stress and inflammatory reaction; regulating autophagy; promoting Ca

conclusionsXinmailong Injection can protect cardiomyocytes and maintain the normal function of the heart in various ways, thus effectively preventing the development of cardiovascular disease. Therefore, Xinmailong Injection has great potential for clinical application, and more basic researches need to be carried out to explore the medicinal value of Xinmailong Injection.

Identifiers

PMID32454845
PMCPMC7219279
OpenAlexW2962832309

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.