Evidence map›Paper›PMID 32454792›Full record

ReviewMediators of inflammation2020

Organ-Protective Effects and the Underlying Mechanism of Dexmedetomidine.

Naren Bao, Bing Tang

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Mediators of inflammation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06570187 (The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients), which is not on this map. Cited by 101 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 8 pooled it
20.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06570187 phase4recruitingnot on this mapstarted 2024, after this paper: background citation

The Effect of Dexmedetomidine on the Renal Functions in Septic Critically Ill Patients

TypeinterventionalSponsorCairo UniversityRan2024 to 2026Enrolled128ConditionsSepsis, Septic Shock, Acute Kidney InjuryArmsDexmedetomidine, Propofol
3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 8 syntheses or guidelines pooled it, 154 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Efficacy and safety of dexmedetomidine for analgesia and sedation in neonates: a systematic review.Journal of perinatology : official journal of the California Perinatal Association · 2024
    Pooled it
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  9. Trial
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  12. Dexmedetomidine Dose-Dependent Modulation of Lung Function and AQP1 Expression During One-Lung Ventilation in Adults Undergoing Thoracoscopic Surgery.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Trial
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  17. [Effects of Dexmedetomidine on the Recovery Quality of Donors Undergoing Pure Laparoscopic Donor Hepatectomy].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Trial
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  20. Trial

41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Naren BaoDepartment of Anesthesiology, The First Hospital of China Medical University, 155 Nanjing North Street, Shenyang, China.ORCID https://orcid.org/0000-0001-7120-4789
Bing TangDepartment of Anesthesiology, The First Hospital of China Medical University, 155 Nanjing North Street, Shenyang, China.ORCID https://orcid.org/0000-0002-1162-9686
First Hospital of China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dexmedetomidine (DEX) is a highly selective

Indexed as

Adenylyl CyclasesAdrenergic alpha-2 Receptor AgonistsAnimalsAnti-Inflammatory AgentsAntioxidantsApoptosisCatecholaminesDexmedetomidineGlutamic AcidGTP-Binding ProteinsHumansHypnotics and SedativesInflammationNeurotoxinsOxidative StressSignal TransductionAdenylyl CyclasesAdrenergic alpha-2 Receptor AgonistsAnti-Inflammatory AgentsAntioxidantsCatecholaminesDexmedetomidineGlutamic AcidGTP-Binding ProteinsHypnotics and SedativesNeurotoxins

Identifiers

PMID32454792
PMCPMC7232715
OpenAlexW3020998558

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.