Evidence map›Paper›PMID 32454701›Full record

ArticleTurkish journal of pharmaceutical sciences2019

Subchronic Toxicity Assessment of Orally Administered Methanol (70%) Seed Extract of

Shazia Tabasum, Swati Khare, Kirti Jain

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Shazia TabasumGovernment Science and Commerce College, Department of Botany, Bhopal, India.ORCID https://orcid.org/0000-0002-6731-1722
Swati KhareGovernment Maharani Laxmi Bai Girls P.G. Autonomous College, Department of Botany, Bhopal, India.ORCID https://orcid.org/
Kirti JainGovernment Science and Commerce College, Department of Botany, Bhopal, India.ORCID https://orcid.org/
Maharani Laxmi Bai Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesMATERIALS AND

methodsA subchronic toxicity experiment was conducted by oral administration of graded doses (200 mg/kg and 400 mg/kg) of test extract daily for 28 days. Signs of toxicity, food and water consumption, body weight, and gross pathology as well as relative organ weight were evaluated. The toxic effects were also assessed using hematological and biochemical data followed by histopathological examination of various internal organs. All data collected were expressed as mean ± standard deviation. ANOVA followed by the Bonferroni test was used for data interpretation and p<0.05 was considered significant.

resultsNo deaths or evident toxic signs were found during the experimental period. There were no significant differences in body weight, gross pathology, organ weight, or food and water consumption between the control and the treated groups. There were no treatment-related differences in hematological or biochemical indices. Moreover, no gross abnormalities or histological alterations were observed.

conclusionThe methanol extract of

Indexed as

Abrus precatoriusbiochemical indiceshematologyhistopathologysubchronic toxicity

Identifiers

PMID32454701
PMCPMC7227984
OpenAlexW2805405319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.