ArticleTurkish journal of pharmaceutical sciences2018
Preparation and Characterization of Caffeine Loaded Liposome and Ethosome Formulations for Transungual Application.
Article in Turkish journal of pharmaceutical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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Who cites it
5 citing papers in PubMed, 13 citations in OpenAlex.
- Skin Penetration of Caffeine and Cafestol using Liposomes: Exploring the Benefits of a Combined Delivery System.AAPS PharmSciTech · 2026Article
- Nanocarriers in Ungual Drug Delivery.Pharmaceutics · 2025Review
- Lipid-based nanoformulations in onychomycosis therapy: addressing challenges of current therapies and advancing treatment.RSC advances · 2025Review
- Methyl gallic acid entrapped ethosomal nano-vesicular system augments cytotoxicity against squamous cell carcinoma.3 Biotech · 2023Article
- Interaction of Caffeine with Model Lipid Membranes.The journal of physical chemistry. B · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesNail plates have a structure that prevents transungual delivery of active agents. This situation makes it difficult to treat nail diseases. MATERIALS AND
methodsIn this study, CF-loaded liposome and ethosome formulations were prepared for ungual application. Formulations were characterized by size, microscopic observation, pH, and entrapment efficiency measurements. The effects of formulations and experimental conditions on nails were tested with characterization of nails before and after
resultsMicroscopic observation confirmed the presence of spherical-structured vesicles. The particle sizes of vesicles were found as 545.3±0.121 nm, 610.2±0.943 nm, 349.5±0.145 nm and 337.9±0.088 nm for liposomes (FI-FII) and ethosomes (FIII- FIV), respectively. The polydispersity index of particles was found under 0.5, and the pH of formulations was around 7. The encapsulation efficiency was found low due to the hydrophilic character of CF. Nail characterization studies showed that the experimental conditions had an effect on the nail plate.
conclusionThe cumulative amount of drug after
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Registered trials
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