ArticleTurkish journal of pharmaceutical sciences2018
The Structural, Crystallinity, and Thermal Properties of pH-responsive Interpenetrating Gelatin/Sodium Alginate-based Polymeric Composites for the Controlled Delivery of Cetirizine HCl.
Article in Turkish journal of pharmaceutical sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Interpenetrating gelatin/sodium alginate hydrogel with controlled PRP lysate delivery for accelerating diabetic wound healing with reduced scarring.RSC advances · 2026Article
- Smart stimuli-responsive drug delivery systems in spotlight of COVID-19.Asian journal of pharmaceutical sciences · 2023Review
- Development and evaluation of pH sensitive semi-interpenetrating networks: assessing the impact of itaconic acid and aloe vera on network swelling and cetirizine release.Frontiers in bioengineering and biotechnology · 2023Article
- In Vitro and Biological Characterization of Dexamethasone Sodium Phosphate Laden pH-Sensitive and Mucoadhesive Hydroxy Propyl β-Cyclodextrin-g-poly(acrylic acid)/Gelatin Semi-Interpenetrating Networks.Gels (Basel, Switzerland) · 2022Article
- Optimization, in vitro release and toxicity evaluation of novel pH sensitive itaconic acid-g-poly(acrylamide)/sterculia gum semi-interpenetrating networks.Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences · 2021Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe present work aimed to design and synthesize pH-sensitive cross-linked Ge/SA hydrogels using different ratios of each polymer, and to investigate the effect of each polymer on dynamic, equilibrium swelling, and MATERIALS AND
methodsThese gelatin and sodium alginate hydrogels were prepared at room temperature through free radical polymerization using glutaraldehyde as a crosslinker. These polymeric composites were used as model systems to envisage various important characterizations. The
resultsThese hydrogels showed maximum swelling at pH 1.2. Zero-order, first-order, Higuchi, and Peppas models were applied to demonstrate the release pattern of drug. The release of drug occurred through non-Fickian diffusion or anomalous mechanism. Porosity was found increased with an increase in concentration of both polymers, and porosity decreased when the concentration of the crosslinker was increased. Gel fraction increased with an increase in concentration of SA, Ge, and glutaraldehyde.
conclusionThe prepared pH sensitive hydrogels can be used as a potential carrier for the sustained delivery of cetirizine hydrochloride.
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Registered trials
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