Evidence map›Paper›PMID 32454619›Full record

ArticleTurkish journal of pharmaceutical sciences2017

Polymorphisms and Protein Expressions of Glutathione S-Transferase M1 and T1 in Non-Small Cell Lung Cancer.

Murat Kiliç, Ahmet Oğuz Ada, Serpil Oğuztüzün, Funda Demirağ, Sezgin Çelik, Pınar Biçakçioğlu, Mümtaz Işcan

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Turkish journal of pharmaceutical sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Murat KiliçAnkara University, Vocational School of Health Services, Department of Pharmacy Services, Ankara, Turkey.
Ahmet Oğuz AdaAnkara University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
Serpil OğuztüzünKırıkkale University, Faculty of Arts and Sciences, Department of Biology, Kırıkkale, Turkey.
Funda DemirağAtatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Clinic of Pathology, Ankara, Turkey.
Sezgin ÇelikYıldız Technical University, Faculty of Arts and Sciences, Department of Molecular Biology and Genetics, İstanbul, Turkey.
Pınar BiçakçioğluAtatürk Chest Diseases and Thoracic Surgery Training and Research Hospital, Clinic of Thoracic Surgery, Ankara, Turkey.
Mümtaz IşcanAnkara University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Ankara, Turkey.
Ankara University · TRYıldız Technical University · TRKırıkkale University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe deletion polymorphisms of glutathione S-transferase (GST) MATERIALS AND

methodsFor protein expression and gene deletion studies, tumor and surrounding tumor free (normal) tissue of 33 patients with NSCLC were used. In paraffin-embedded tissues, immunohistochemistry was used to detect protein expressions, and multiplex polymerase chain reaction amplification was used to identify gene deletions.

results

conclusionThese results show that a) there is an association between gene deletions and protein expressions of

Indexed as

GSTM1GSTT1non-small cell lung carcinomapolymorphismprotein expression

Identifiers

PMID32454619
PMCPMC7227930
OpenAlexW2770366702

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.