Evidence map›Paper›PMID 32454580›Full record

ArticleOrganic process research & development2020

Crystallization-Induced Diastereoisomer Transformation of Dihydroartemisinic Aldehyde with the Betti Base.

Andrea Zanetti, Pauline Chaumont-Olive, Geoffrey Schwertz, Marllon Nascimento de Oliveira, Mario Andrés Gomez Fernandez, Zacharias Amara, Janine Cossy

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Organic process research & development, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Andrea ZanettiMolecular, Macromolecular Chemistry and Materials, ESPCI Paris/CNRS/PSL Research University, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Pauline Chaumont-OliveMolecular, Macromolecular Chemistry and Materials, ESPCI Paris/CNRS/PSL Research University, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Geoffrey SchwertzMolecular, Macromolecular Chemistry and Materials, ESPCI Paris/CNRS/PSL Research University, 10 rue Vauquelin, 75231 Paris Cedex 05, France.
Marllon Nascimento de OliveiraEquipe Chimie Moléculaire, Laboratoire de Génomique, Bioinformatique et Chimie Moléculaire (GBCM), EA 7528, Conservatoire national des arts et métiers, HESAM Université, 2 rue Conté, 75003 Paris Cedex 03, France.
Mario Andrés Gomez FernandezEquipe Chimie Moléculaire, Laboratoire de Génomique, Bioinformatique et Chimie Moléculaire (GBCM), EA 7528, Conservatoire national des arts et métiers, HESAM Université, 2 rue Conté, 75003 Paris Cedex 03, France.
Zacharias AmaraEquipe Chimie Moléculaire, Laboratoire de Génomique, Bioinformatique et Chimie Moléculaire (GBCM), EA 7528, Conservatoire national des arts et métiers, HESAM Université, 2 rue Conté, 75003 Paris Cedex 03, France.
Janine CossyMolecular, Macromolecular Chemistry and Materials, ESPCI Paris/CNRS/PSL Research University, 10 rue Vauquelin, 75231 Paris Cedex 05, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Artemisinin is an important drug to fight malaria. It is produced either by extraction or via a semisynthetic route involving enzyme engineering. A key intermediate to produce artemisinin by the enzymatic route is dihydroartemisinic aldehyde (

Identifiers

PMID32454580
PMCPMC7237042

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.