Evidence map›Paper›PMID 32454157›Full record

ReviewLife sciences2020

Crosstalk between endoplasmic reticulum stress and anti-viral activities: A novel therapeutic target for COVID-19.

Aditi Banerjee, Steven J Czinn, Russel J Reiter, Thomas G Blanchard

Open access · bronzeAbstract readReview
In one paragraph

Review in Life sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
26.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 121 citations in OpenAlex.

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  16. ERC-BiP Functional Protein Pathway for Assessing Endoplasmic Reticulum Stress Induced by SARS-CoV-2 Replication after Cell Invasion.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  17. Review
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Aditi BanerjeeDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA. Electronic address: aditi.banerjee@som.umaryland.edu.
Steven J CzinnDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Russel J ReiterDepartment of Cell Systems and Anatomy, UT Health San Antonio, San Antonio, TX 78229, USA.
Thomas G BlanchardDepartment of Pediatrics, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
University of Maryland, Baltimore · USThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The outbreak of COVID-19 caused by 2019-nCov/SARS-CoV-2 has become a pandemic with an urgent need for understanding the mechanisms and identifying a treatment. Viral infections including SARS-CoV are associated with increased levels of reactive oxygen species, disturbances of Ca

Indexed as

Activating Transcription Factor 6Antiviral AgentsBetacoronavirusCoronavirus InfectionsCOVID-19DiterpenesDrug SynergismeIF-2 KinaseEndoplasmic Reticulum StressEndoribonucleasesHumansMelatoninMolecular Targeted TherapyPandemicsPneumonia, ViralProtein Serine-Threonine KinasesActivating Transcription Factor 6andrographolideAntiviral AgentsATF6 protein, humanDiterpenesEIF2AK3 protein, humaneIF-2 KinaseEndoribonucleasesERN1 protein, humanMelatoninProtein Serine-Threonine Kinases2019-nCov/SARS-CoV-2AndrographolideCOVID-19Endoplasmic reticulum stressMelatoninUnfolded protein response

Identifiers

PMID32454157
PMCPMC7245231
OpenAlexW3026354710

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.