Evidence map›Paper›PMID 32454135›Full record

ArticleBrain, behavior, and immunity2020

Genetic variants drive altered epigenetic regulation of endotoxin response in BTBR macrophages.

Annie Vogel Ciernia, Verena M Link, Milo Careaga, Janine M LaSalle, Paul Ashwood

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Metabolic Endotoxemia: From the Gut to Neurodegeneration.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annie Vogel CierniaDepartment Biochemistry and Molecular Biology, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver V6T2A1, Canada. Electronic address: annie.ciernia@ubc.ca.
Verena M LinkMetaorganism Immunity Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
Milo CareagaDepartment of Medical Microbiology and Immunology, MIND Institute, Genome Center, University of California, Davis, CA 95616, USA.
Janine M LaSalleDepartment of Medical Microbiology and Immunology, MIND Institute, Genome Center, University of California, Davis, CA 95616, USA.
Paul AshwoodDepartment of Medical Microbiology and Immunology, MIND Institute, Genome Center, University of California, Davis, CA 95616, USA.

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
Rodent Behavior CoreU54HD079125 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CRAWLEY, JACQUELINE N · 2013 to 2019
$8.5M
Neuroimmune interactions in Rett syndromeR01AA027075 · NIAAA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LASALLE, JANINE M · 2018 to 2022
$2.9M
Immune regulation and autismR01MH118209 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ASHWOOD, PAUL · 2019 to 2023
$2.0M
Immune regulation and gastrointestinal co-morbidity in autism spectrum disordersR01HD090214 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ASHWOOD, PAUL · 2018 to 2022
$1.9M
The Role of MeCP2 in Rett SyndromeR01NS081913 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LASALLE, JANINE M · 2012 to 2016
$1.9M
Methylomic and genomic impacts of organic pollutants in Dup15q syndromeR01ES021707 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LASALLE, JANINE M · 2012 to 2016
$1.8M
Pacific Biosciences PacBio RS Single Molecule Real Time SequencerS10OD018174 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI ROKHSAR, DANIEL SOLEYMAN · 2014 to 2014
$600k
The effects of environmental air pollutants on maternal allergic asthma and its neurobiological consequencesR21ES025560 · NIEHS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ASHWOOD, PAUL · 2017 to 2018
$432k
Maternal asthma and brain developmentR21MH116383 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ASHWOOD, PAUL · 2018 to 2019
$432k
Mapping Multi-Omics Networks in Microglia Across Autism ModelsK01MH116389 · NIMH · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CIERNIA, ANNIE VOGEL · 2018 to 2018
$106k
NIAAA NIH HHS R01 AA027075NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD090214NICHD NIH HHS U54 HD079125NIEHS NIH HHS R01 ES021707NIEHS NIH HHS R21 ES025560NIH HHS S10 OD018174NIMH NIH HHS K01 MH116389NIMH NIH HHS R01 MH118209NIMH NIH HHS R21 MH116383NINDS NIH HHS R01 NS081913
6 · The paper itself

Abstract

The BTBR T

Indexed as

EndotoxinsEpigenesis, GeneticAnimalsDisease Models, AnimalMacrophagesMiceMice, Inbred C57BLEndotoxins

Identifiers

PMID32454135
PMCPMC7572655

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.