ArticleProceedings. Biological sciences2020
'What I cannot create, I do not understand': functionally validated synergism of metabolic and target site insecticide resistance.
Article in Proceedings. Biological sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 76 citations in OpenAlex.
- Article
- Synergistic action of different molecular mechanisms causes striking levels of insecticide resistance in the malaria vectorProceedings of the National Academy of Sciences of the United States of America · 2026Article
- Insecticide resistance level and geographical distribution of target-site mutations in field collections of the house fly (Musca domestica) from Türkiye.Ecotoxicology (London, England) · 2026Article
- Predictive chemoproteomics and functional validation reveal Coeae6g-mediated insecticide cross-resistance in the malaria vector Anopheles gambiae.Nature communications · 2025Article
- Review
- CRISPR/Cas Technology in Insect Insecticide Resistance.Insects · 2025Review
- Article
- Heat shock proteins, thermotolerance, and insecticide resistance in mosquitoes.Frontiers in insect science · 2024Review
- The power of Drosophila genetics in studying insect toxicology and chemical ecology.Crop health · 2023Review
- Article
- Time-series analysis of transcriptomic changes due to permethrin exposure reveals that Aedes aegypti undergoes detoxification metabolism over 24 h.Scientific reports · 2023Article
- TransgenicToxins · 2023Article
- Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest.Evolutionary applications · 2023Article
- Article
- Using an antimalarial in mosquitoes overcomes Anopheles and Plasmodium resistance to malaria control strategies.PLoS pathogens · 2022Article
- Characterization of a novel pesticide transporter and P-glycoprotein orthologues inProceedings. Biological sciences · 2022Article
- Mosquito population structure, pathogen surveillance and insecticide resistance monitoring in urban regions of Crete, Greece.PLoS neglected tropical diseases · 2022Article
- Assessing the anti-resistance potential of public health vaporizer formulations and insecticide mixtures with pyrethroids using transgenic Drosophila lines.Parasites & vectors · 2021Article
- CRISPR-mediated knock-in of transgenes into the malaria vector Anopheles funestus.G3 (Bethesda, Md.) · 2021Article
- Chemical control and insecticide resistance status of sand fly vectors worldwide.PLoS neglected tropical diseases · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The putative synergistic action of target-site mutations and enhanced detoxification in pyrethroid resistance in insects has been hypothesized as a major evolutionary mechanism responsible for dramatic consequences in malaria incidence and crop production. Combining genetic transformation and CRISPR/Cas9 genome modification, we generated transgenic
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.