Evidence map›Paper›PMID 32453879›Full record

ReviewMedical physics2020

Multi-energy computed tomography and material quantification: Current barriers and opportunities for advancement.

Megan C Jacobsen, Sara L Thrower, Rachel B Ger, Shuai Leng, Laurence E Court, Kristy K Brock, Eric P Tamm, Erik N K Cressman, Dianna D Cody, Rick R Layman

Open access · greenAbstract readReview
In one paragraph

Review in Medical physics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Long-term quantitative stability of a first-generation dual-source photon-counting CT.Conference proceedings. International Conference on Image Formation in X-Ray Computed Tomography · 2024
    Article
  12. Review
  13. Article
  14. Medical Radiology: Current Progress.Diagnostics (Basel, Switzerland) · 2023
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Megan C JacobsenDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Sara L ThrowerDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Rachel B GerDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Shuai LengDepartment of Radiology, Mayo Clinic, Rochester, MN, 55905, USA.
Laurence E CourtDepartment of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Kristy K BrockDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Eric P TammDepartment of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Erik N K CressmanDepartment of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Dianna D CodyDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
Rick R LaymanDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
The University of Texas MD Anderson Cancer Center · USMayo Clinic in Arizona · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
Photon-Counting Spectral CT to Reduce Dose and Detect Early Vascular DiseaseR01EB016966 · NIBIB · MAYO CLINIC ROCHESTER · PI MCCOLLOUGH, CYNTHIA H · 2013 to 2017
$5.1M
Simultaneous Thermal and Osmotic Stresses in Tumor Ablation: Imaging and BiologyR01CA201127 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CRESSMAN, ERIK N · 2016 to 2020
$2.3M
Optimization and Evaluation of Anatomical Models of Liver Radiation ResponseR01CA221971 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI BROCK, KRISTY · 2018 to 2022
$1.8M
Understanding Uncertainties in Radiomics StudiesR21CA216572 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI COURT, LAURENCE E · 2017 to 2018
$313k
Helen Black Image Guidance FundNASA 80NSSC18K1639National Institutes of Health Cancer Center Support Grant P30CA016672NCI NIH HHS P30 CA016672NCI NIH HHS R01 CA201127NCI NIH HHS R01CA201127NCI NIH HHS R01 CA221971NCI NIH HHS R01CA221971NCI NIH HHS R21 CA216572NCI NIH HHS R21CA216572NIBIB NIH HHS R01 EB016966NIBIB NIH HHS R01EB016966
6 · The paper itself

Abstract

Computed tomography (CT) technology has rapidly evolved since its introduction in the 1970s. It is a highly important diagnostic tool for clinicians as demonstrated by the significant increase in utilization over several decades. However, much of the effort to develop and advance CT applications has been focused on improving visual sensitivity and reducing radiation dose. In comparison to these areas, improvements in quantitative CT have lagged behind. While this could be a consequence of the technological limitations of conventional CT, advanced dual-energy CT (DECT) and photon-counting detector CT (PCD-CT) offer new opportunities for quantitation. Routine use of DECT is becoming more widely available and PCD-CT is rapidly developing. This review covers efforts to address an unmet need for improved quantitative imaging to better characterize disease, identify biomarkers, and evaluate therapeutic response, with an emphasis on multi-energy CT applications. The review will primarily discuss applications that have utilized quantitative metrics using both conventional and DECT, such as bone mineral density measurement, evaluation of renal lesions, and diagnosis of fatty liver disease. Other topics that will be discussed include efforts to improve quantitative CT volumetry and radiomics. Finally, we will address the use of quantitative CT to enhance image-guided techniques for surgery, radiotherapy and interventions and provide unique opportunities for development of new contrast agents.

Indexed as

PhotonsTomography, X-Ray ComputedTomographydual-energy computed tomographyphoton-counting detector computed tomographyquantitative computed tomography

Identifiers

PMID32453879
PMCPMC8495770
OpenAlexW3030305842

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.