Evidence map›Paper›PMID 32453687›Full record

GuidelineBlood transfusion = Trasfusione del sangue2020

Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.

Patrizia Accorsi, Pierluigi Berti, Vincenzo de Angelis, Giustina De Silvestro, Luca Mascaretti, Angelo Ostuni, Italian Society for Transfusion Medicine and Immunohaematology (SIMTI) and the Italian Society for Haemapheresis and Cell Manipulation (SIdEM)

Open access · greenAbstract readPractice Guideline
In one paragraph

Guideline in Blood transfusion = Trasfusione del sangue, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Preparedness and activities of the anti-SARS-CoV-2 convalescent plasma bank in the Veneto region (Italy): An organizational model for future emergencies.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2021
    Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Patrizia AccorsiDepartment of Haematology, Transfusion Medicine and Biotechnologies, Ospedale Civile, Pescara, Italy.
Pierluigi BertiImmunohaematology and Transfusion Medicine, "Umberto Parini" Hospital, Aosta, Italy.
Vincenzo de AngelisTransfusion Medicine Department, Azienda Sanitaria Universitaria "Friuli Centrale", Udine, Italy.
Giustina De SilvestroBlood Transfusion Service, University Hospital of Padua, Padua, Italy.
Luca MascarettiTransfusion Medicine Department, Azienda Sanitaria Universitaria "Giuliano Isontina", Trieste, Italy.
Angelo OstuniTransfusional Medicine Unit, University-Hospital Policlinico, Bari, Italy.
Italian Society for Transfusion Medicine and Immunohaematology (SIMTI) and the Italian Society for Haemapheresis and Cell Manipulation (SIdEM)
Azienda Sanitaria Universitaria Integrata di Trieste · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Passive immunotherapy with plasma derived from convalescent patients recovering from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that blood establishments are ready to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution, and control of product use. This Position paper aims to give recommendations on the biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.

Indexed as

Antibodies, ViralBetacoronavirusBlood BanksBlood DonorsCoronavirus InfectionsCOVID-19COVID-19 SerotherapyEuropeHumansImmunization, PassiveImmunization ScheduleInformed ConsentItalyPandemicsPlasmaPneumonia, ViralAntibodies, Viral

Identifiers

PMID32453687
PMCPMC7250681
OpenAlexW3031223156

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.