Evidence map›Paper›PMID 32453626›Full record

ArticleRNA biology2020

Specificities and functional coordination between the two Cas6 maturation endonucleases in

Viktoria Reimann, Marcus Ziemann, Hui Li, Tao Zhu, Juliane Behler, Xuefeng Lu, Wolfgang R Hess

Open access · bronzeAbstract read
In one paragraph

Article in RNA biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Characterization of Five CRISPR Systems inInternational journal of molecular sciences · 2025
    Article
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  8. CRISPR Arrays Away fromThe CRISPR journal · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Viktoria ReimannFaculty of Biology, Institute of Biology III, University of Freiburg , Germany.
Marcus ZiemannFaculty of Biology, Institute of Biology III, University of Freiburg , Germany.
Hui LiKey Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences , Qingdao, China.
Tao ZhuKey Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences , Qingdao, China.ORCID 0000-0003-0830-2735
Juliane BehlerFaculty of Biology, Institute of Biology III, University of Freiburg , Germany.
Xuefeng LuKey Laboratory of Biofuels, Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences , Qingdao, China.ORCID 0000-0002-0570-9196
Wolfgang R HessFaculty of Biology, Institute of Biology III, University of Freiburg , Germany.ORCID 0000-0002-5340-3423
University of Freiburg · DEChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many bacteria and archaea possess an RNA-guided adaptive and inheritable immune system that consists of clustered regularly interspaced short palindromic repeats (CRISPRs) and CRISPR-associated (Cas) proteins. In most CRISPR-Cas systems, the maturation of CRISPR-derived small RNAs (crRNAs) is essential for functionality. Cas6 endonucleases function as the most frequent CRISPR RNA maturation enzymes. In the cyanobacterium

Indexed as

CRISPR-Cas SystemsAnabaenaCRISPR-Associated ProteinsEndodeoxyribonucleasesEnzyme ActivationGene Expression ProfilingGene Expression Regulation, BacterialRNA, BacterialRNA Processing, Post-TranscriptionalRNA, Small UntranslatedSequence DeletionSubstrate SpecificityTranscription, GeneticTranscriptomeCRISPR-Associated ProteinsEndodeoxyribonucleasesRNA, BacterialRNA, Small UntranslatedArray fragmentationCas6 enzymesCRISPR-CAS systemscyanobacteria

Identifiers

PMID32453626
PMCPMC7549632
OpenAlexW3031943262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.