ArticleAndrology2021
SARS-CoV-2 presence in seminal fluid: Myth or reality.
Article in Andrology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Pooled it
- Pooled it
- Urological complications of COVID-19: a systematic review.International braz j urol : official journal of the Brazilian Society of UrologyPooled it
- COVID-19 and Oncofertility: No SARS-CoV-2 in Semen but Inflammation Seems to Affect Sperm Parameters.Journal of medical virology · 2024Article
- Investigating the mode of transmission of COVID-19 through genital secretions, semen, the birth canal, and lactation: A systematic review.Journal of education and health promotion · 2024Article
- SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023Review
- Review
- Review
- Validation of a SARS-CoV-2 RT-PCR assay: a requirement to evaluate viral contamination in human semen.Reproductive biomedicine online · 2022Article
- 4BNT162b2 mRNA COVID-19 vaccine and semen: What do we know?Andrology · 2022Article
- COVID-19 Infections in Gonads: Consequences on Fertility?Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2022Review
- The potential impact of COVID-19 on male reproductive health.Journal of endocrinological investigation · 2022Review
- Covid-19 and its implications for the provision of gynecological services globally.European journal of obstetrics, gynecology, and reproductive biology · 2022Article
- Evaluation of mid- and long-term impact of COVID-19 on male fertility through evaluating semen parameters.Translational andrology and urology · 2022Article
- Impacts of COVID-19 and SARS-CoV-2 on male reproductive function: a systematic review and meta-analysis protocol.BMJ open · 2022Article
- Effects of SARS-CoV-2 infection on human reproduction.Journal of molecular cell biology · 2021Review
- Molecular diagnosis of SARS-CoV-2 in seminal fluid.Journal of endocrinological investigation · 2021Article
- The presence of SARS-CoV-2 virus in semen samples of patients with COVID-19 pneumonia.Andrologia · 2021Article
- Short-term effects of COVID-19 on semen parameters: A multicenter study of 69 cases.Andrology · 2021Article
- "Mask up to keep it up": Preliminary evidence of the association between erectile dysfunction and COVID-19.Andrology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Great concerns have been raised on SARS-CoV-2 impact on men's andrological well-being, and one of the critically unanswered questions is whether it is present or not in the seminal fluid of infected subjects. The expression of ACE2 and TMPRSS2 in the testis and in the male genital tract allows speculations about a possible testicular involvement during the infection, possibly mediated by local and/or systemic inflammation that might allow a high viral load to overcome the hemato-testicular barrier. To date, few investigations have been carried out to ascertain the presence of SARS-CoV-2 in the seminal fluid with contrasting results. Furthermore, the cumulative number of subjects is far too low to answer the question unambiguously. Therefore, great caution is still needed when evaluating this data; otherwise, we risk unleashing unmotivated concerns in the scientific world with troublesome consequences in reproductive medicine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.