Evidence map›Paper›PMID 32452648›Full record

ArticleTransboundary and emerging diseases2020

Estimating the serial interval of the novel coronavirus disease (COVID-19) based on the public surveillance data in Shenzhen, China, from 19 January to 22 February 2020.

Kai Wang, Shi Zhao, Ying Liao, Tiantian Zhao, Xiaoyan Wang, Xueliang Zhang, Haiyan Jiao, Huling Li, Yi Yin, Maggie H Wang and 3 more

Abstract read
In one paragraph

Article in Transboundary and emerging diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. VIBES: A multiscale modeling approach integrating within-host and between-hosts dynamics in epidemics.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Attach importance of the bootstrapEpidemiology and infection · 2021
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  14. Subcritical Transmission in the Early Stage of COVID-19 in Korea.International journal of environmental research and public health · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kai WangDepartment of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China.
Shi ZhaoJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.ORCID https://orcid.org/0000-0001-8722-6149
Ying LiaoCollege of Public Health, Xinjiang Medical University, Urumqi, China.
Tiantian ZhaoCollege of Public Health, Xinjiang Medical University, Urumqi, China.
Xiaoyan WangCollege of Public Health, Xinjiang Medical University, Urumqi, China.
Xueliang ZhangDepartment of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China.
Haiyan JiaoCollege of Public Health, Xinjiang Medical University, Urumqi, China.
Huling LiCollege of Public Health, Xinjiang Medical University, Urumqi, China.
Yi YinDepartment of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China.
Maggie H WangJC School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong, China.
Li XiaoCollege of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Lei WangDepartment of Medical Engineering and Technology, Xinjiang Medical University, Urumqi, China.
Daihai HeDepartment of Applied Mathematics, Hong Kong Polytechnic University, Hong Kong, China.ORCID https://orcid.org/0000-0003-3253-654X

Funding

Alibaba-Hong Kong Polytechnic University Collaborative Research project P0031768National Natural Science Foundation of China 11961071Research Grants Council, University Grants Committee 15205119
6 · The paper itself

Abstract

The novel coronavirus disease (COVID-19) poses a serious threat to global public health and economics. Serial interval (SI), time between the onset of symptoms of a primary case and a secondary case, is a key epidemiological parameter. We estimated SI of COVID-19 in Shenzhen, China based on 27 records of transmission chains. We adopted three parametric models: Weibull, lognormal and gamma distributions, and an interval-censored likelihood framework. The three models were compared using the corrected Akaike information criterion (AICc). We also fitted the epidemic curve of COVID-19 to the logistic growth model to estimate the reproduction number. Using a Weibull distribution, we estimated the mean SI to be 5.9 days (95% CI: 3.9-9.6) with a standard deviation (SD) of 4.8 days (95% CI: 3.1-10.1). Using a logistic growth model, we estimated the basic reproduction number in Shenzhen to be 2.6 (95% CI: 2.4-2.8). The SI of COVID-19 is relatively shorter than that of SARS and MERS, the other two betacoronavirus diseases, which suggests the iteration of the transmission may be rapid. Thus, it is crucial to isolate close contacts promptly to effectively control the spread of COVID-19.

Indexed as

Basic Reproduction NumberEpidemiological MonitoringPopulation SurveillanceAdolescentAdultAgedChildChild, PreschoolChinaCOVID-19FemaleHumansMaleMiddle AgedSARS-CoV-2Young Adultbasic reproduction numbercoronavirus diseaseCOVID-19outbreakserial intervalShenzhen

Identifiers

PMID32452648
PMCPMC7283843

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.